Auditory Development and Restoration Program,
National Institute on Deafness and Other Communication Disorders,
Auditory Development and Restoration Program, National Institute on Deafness and Other Communication Disorders
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Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear.
Nature communications Oct, 2015 | Pubmed ID: 26469390
mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2017 | Pubmed ID: 28847925
Molecular architecture underlying fluid absorption by the developing inner ear.
eLife 10, 2017 | Pubmed ID: 28994389
CDC14A phosphatase is essential for hearing and male fertility in mouse and human.
Human molecular genetics Mar, 2018 | Pubmed ID: 29293958
Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10).
Scientific reports Mar, 2018 | Pubmed ID: 29535325
Mutational and phenotypic spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome.
Human mutation Feb, 2019 | Pubmed ID: 30461122
Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis.
Frontiers in molecular neuroscience , 2019 | Pubmed ID: 31920542
Noncoding Microdeletion in Mouse Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2020 | Pubmed ID: 32152201
Applications of single-cell sequencing for the field of otolaryngology: A contemporary review.
Laryngoscope investigative otolaryngology Jun, 2020 | Pubmed ID: 32596483
Mouse Models of Human Pathogenic Variants of Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness.
Genes Sep, 2020 | Pubmed ID: 32987832
Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea.
Scientific reports Oct, 2020 | Pubmed ID: 33093630
Identification of Potential Meniere's Disease Targets in the Adult Stria Vascularis.
Frontiers in neurology , 2021 | Pubmed ID: 33613436
New insights into Perrault syndrome, a clinically and genetically heterogeneous disorder.
Human genetics Apr, 2022 | Pubmed ID: 34338890
Utilizing Single Cell RNA-Sequencing to Implicate Cell Types and Therapeutic Targets for SSNHL in the Adult Cochlea.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology Dec, 2021 | Pubmed ID: 34510123
Single-Cell RNA-Seq of Cisplatin-Treated Adult Stria Vascularis Identifies Cell Type-Specific Regulatory Networks and Novel Therapeutic Gene Targets.
Frontiers in molecular neuroscience , 2021 | Pubmed ID: 34566577
Repurposable Drugs That Interact with Steroid Responsive Gene Targets for Inner Ear Disease.
Biomolecules Nov, 2022 | Pubmed ID: 36358991
Editorial: Autoinflammation of the inner ear.
Frontiers in neurology , 2022 | Pubmed ID: 36388231
The role of the stria vascularis in neglected otologic disease.
Hearing research Feb, 2023 | Pubmed ID: 36584545
Variants of LRP2, encoding a multifunctional cell-surface endocytic receptor, associated with hearing loss and retinal dystrophy.
Clinical genetics Feb, 2023 | Pubmed ID: 36807241
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