Dirk Bumann

Has nature already identified all useful antibacterial targets?

System-level analysis of Salmonella metabolism during infection.

Pathogen proteomes during infection: A basis for infection research and novel control strategies.

A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2.

Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota.

Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic.

Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination.

Extensive in vivo resilience of persistent Salmonella.

Immunity to intracellular Salmonella depends on surface-associated antigens.

Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway.

Parallel exploitation of diverse host nutrients enhances Salmonella virulence.

Disparate impact of oxidative host defenses determines the fate of Salmonella during systemic infection in mice.

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion.

Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth.

Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy.

Identification of Protective Antigens for Vaccination against Systemic Salmonellosis.

Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry.

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

Heterogeneous host-pathogen encounters: act locally, think globally.

Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development.

Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality.

A Novel Genome-Editing Platform for Drug-Resistant Acinetobacter baumannii Reveals an AdeR-Unrelated Tigecycline Resistance Mechanism.

Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage.

Intracellular Salmonella metabolism.

Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling.

Heterogeneity of Salmonella-host interactions in infected host tissues.

Structural basis for maintenance of bacterial outer membrane lipid asymmetry.

Editorial overview: Bacterial systems biology.

Correction for Wu et al., "Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling".

TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates.

The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa.

A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii.

Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity.

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains.

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Single-Cell Metabolism and Stress Responses in Complex Host Tissues.

Definitions and guidelines for research on antibiotic persistence.

Publisher Correction: Definitions and guidelines for research on antibiotic persistence.

Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates.

Non-specific interference of cobalt with siderophore-dependent iron uptake pathways.

Antibiotic chemotherapy against heterogeneous pathogen populations in complex host tissues.

Host resistance factor SLC11A1 restricts growth through magnesium deprivation.

Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.

Classical Activation of Macrophages Leads to Lipid Droplet Formation Without Fatty Acid Synthesis.

Efficient dual-negative selection for bacterial genome editing.

Dynamics in protein translation sustaining T cell preparedness.

Single-cell reporters for pathogen responses to antimicrobial host attacks.

Regulation of chaperone function by coupled folding and oligomerization.

Molecular reprogramming and phenotype switching in lead to high antibiotic persistence and affect therapy success.

Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack.

Ferritin H deficiency deteriorates cellular iron handling and worsens Salmonella typhimurium infection by triggering hyperinflammation.

Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in .

Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site.

Tissue compartmentalization enables persistence during chemotherapy.

Making Antimicrobial Susceptibility Testing More Physiologically Relevant with Bicarbonate?

Plant-Derived Catechols Are Substrates of TonB-Dependent Transporters and Sensitize Pseudomonas aeruginosa to Siderophore-Drug Conjugates.

Importance of aspartyl protease 5 in the establishment of the intracellular niche during acute and chronic infection of Toxoplasma gondii.

Zebrafish Larvae as an Model for Antimicrobial Activity Tests against Intracellular .

Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.