Department of Molecular Pharmacology & Therapeutics
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Signal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spiking.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11739373
H(2)O(2)-induced Ca(2+) overload in NRVM involves ERK1/2 MAP kinases: role for an NHE-1-dependent pathway.
American journal of physiology. Heart and circulatory physiology Aug, 2002 | Pubmed ID: 12124207
Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.
Journal of molecular and cellular cardiology Sep, 2003 | Pubmed ID: 12967635
Low voltage-activated calcium channels in vascular smooth muscle: T-type channels and AVP-stimulated calcium spiking.
American journal of physiology. Heart and circulatory physiology Feb, 2005 | Pubmed ID: 15498818
Evidence against reciprocal regulation of Ca2+ entry by vasopressin in A7r5 rat aortic smooth-muscle cells.
The Biochemical journal May, 2005 | Pubmed ID: 15603557
Protein-protein interactions in vasopressin signal transduction: new evidence for cytoskeletal dynamics.
The Journal of the American Osteopathic Association Jan, 2005 | Pubmed ID: 15710669
Pharmacological and electrophysiological characterization of store-operated currents and capacitative Ca(2+) entry in vascular smooth muscle cells.
The Journal of pharmacology and experimental therapeutics May, 2006 | Pubmed ID: 16415091
Vasopressin stimulates action potential firing by protein kinase C-dependent inhibition of KCNQ5 in A7r5 rat aortic smooth muscle cells.
American journal of physiology. Heart and circulatory physiology Mar, 2007 | Pubmed ID: 17071736
Vasopressin-induced vasoconstriction: two concentration-dependent signaling pathways.
Journal of applied physiology (Bethesda, Md. : 1985) Apr, 2007 | Pubmed ID: 17204577
Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance.
The Journal of pharmacology and experimental therapeutics May, 2008 | Pubmed ID: 18272810
Cardiovascular KCNQ (Kv7) potassium channels: physiological regulators and new targets for therapeutic intervention.
Molecular pharmacology Nov, 2008 | Pubmed ID: 18684841
Opposite regulation of KCNQ5 and TRPC6 channels contributes to vasopressin-stimulated calcium spiking responses in A7r5 vascular smooth muscle cells.
Cell calcium Apr, 2009 | Pubmed ID: 19246091
Labour pains: giving birth to new mechanisms for the regulation of myometrial contractility.
The Journal of physiology May, 2009 | Pubmed ID: 19443849
Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles.
Molecular pharmacology Nov, 2009 | Pubmed ID: 19605525
Novel Actions of Nonsteroidal Anti-Inflammatory Drugs on Vascular Ion Channels: Accounting for Cardiovascular Side Effects and Identifying New Therapeutic Applications.
Molecular and cellular pharmacology , 2010 | Pubmed ID: 20689646
Diclofenac distinguishes among homomeric and heteromeric potassium channels composed of KCNQ4 and KCNQ5 subunits.
Molecular pharmacology Jan, 2011 | Pubmed ID: 20876743
Vascular KCNQ channels in humans: the sub-threshold brake that regulates vascular tone?
British journal of pharmacology Jan, 2011 | Pubmed ID: 21188789
Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery.
British journal of pharmacology Sep, 2011 | Pubmed ID: 21323904
Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy.
American journal of physiology. Lung cellular and molecular physiology Jan, 2012 | Pubmed ID: 21964407
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