Department of Cardiovascular and Metabolic Sciences,
Lerner Research Institute,
Taussig Cancer Institute,
Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute
Keith R. McCrae has not added Biography.
If you are Keith R. McCrae and would like to personalize this page please email our Author Liaison for assistance.
Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice.
The Journal of clinical investigation May, 2008 | Pubmed ID: 18431509
Impaired fibrinolysis in the antiphospholipid syndrome.
Current rheumatology reports Feb, 2010 | Pubmed ID: 20425534
Blind men and the APS.
Blood Oct, 2010 | Pubmed ID: 20966177
Thrombocytopenia in pregnancy.
Hematology. American Society of Hematology. Education Program , 2010 | Pubmed ID: 21239825
Sutton's law and anti-β₂GPI antibodies.
Blood Mar, 2011 | Pubmed ID: 21436079
Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors.
Blood Jun, 2011 | Pubmed ID: 21482710
Immune thrombocytopenia: no longer 'idiopathic'.
Cleveland Clinic journal of medicine Jun, 2011 | Pubmed ID: 21632906
RhIG for the treatment of immune thrombocytopenia: consensus and controversy (CME).
Transfusion May, 2012 | Pubmed ID: 21981825
Restoration of glycemic control in patients with type 2 diabetes mellitus after bariatric surgery is associated with reduction in microparticles.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery , 2013 | Pubmed ID: 22093380
A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies.
Blood Jan, 2012 | Pubmed ID: 22106343
Chimeric glutathione S-transferases containing inserts of kininogen peptides: potential novel protein therapeutics.
The Journal of biological chemistry May, 2012 | Pubmed ID: 22577144
Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation.
Blood Nov, 2012 | Pubmed ID: 22936662
Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.
Blood Nov, 2012 | Pubmed ID: 22966172
Management and outcomes for patients with TTP: analysis of 100 cases at a single institution.
American journal of hematology Jul, 2013 | Pubmed ID: 23605996
Immune thrombocytopenia.
Hematology/oncology clinics of North America Jun, 2013 | Pubmed ID: 23714309
Anti-β2GPI antibodies stimulate endothelial cell microparticle release via a nonmuscle myosin II motor protein-dependent pathway.
Blood Nov, 2013 | Pubmed ID: 23954892
The least of 3 evils: exposure to red blood cell transfusion, anemia, or both?
The Journal of thoracic and cardiovascular surgery Dec, 2013 | Pubmed ID: 23998782
Better late than never?
Blood Sep, 2013 | Pubmed ID: 24030254
Risk stratification strategies for cancer-associated thrombosis: an update.
Thrombosis research May, 2014 | Pubmed ID: 24862143
Rituximab for treatment of inhibitors in haemophilia A. A Phase II study.
Thrombosis and haemostasis Sep, 2014 | Pubmed ID: 24919980
Recent advances in the antiphospholipid antibody syndrome.
Current opinion in hematology Sep, 2014 | Pubmed ID: 25023470
Antiplatelet antibodies in oxaliplatin-induced immune thrombocytopenia.
JRSM open Jun, 2014 | Pubmed ID: 25057402
Symptomatic and incidental venous thromboembolic disease are both associated with mortality in patients with prostate cancer.
PloS one , 2014 | Pubmed ID: 25126949
Circulating microparticles in patients with antiphospholipid antibodies: characterization and associations.
Thrombosis research Jan, 2015 | Pubmed ID: 25467081
Lipocalin-2 released in response to cerebral ischaemia mediates reperfusion injury in mice.
Journal of cellular and molecular medicine Jul, 2015 | Pubmed ID: 25702801
Increased morbidity during long-term follow-up of survivors of thrombotic thrombocytopenic purpura.
American journal of hematology Oct, 2015 | Pubmed ID: 26228638
The antiphospholipid syndrome: still an enigma.
Hematology. American Society of Hematology. Education Program , 2015 | Pubmed ID: 26637701
Recurrent venous thromboembolism in glioblastoma.
Thrombosis research Jan, 2016 | Pubmed ID: 26657302
FcγRIII in ITP: it ain't over 'til it's over.
Blood Jan, 2016 | Pubmed ID: 26744437
Predictors of recurrent venous thromboembolism and bleeding on anticoagulation.
Thrombosis research Apr, 2016 | Pubmed ID: 27067987
Treatment of chronic immune thrombocytopenia in children with romiplostim.
Lancet (London, England) Jul, 2016 | Pubmed ID: 27103125
Novel role for p56/Lck in regulation of endothelial cell survival and angiogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2016 | Pubmed ID: 27402674
Evaluation of US prescription patterns: Are treatment guidelines for cancer-associated venous thromboembolism being followed?
Thrombosis research Sep, 2016 | Pubmed ID: 27485998
Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group.
Cancer research Jul, 2016 | Pubmed ID: 27527638
Blind men and the refractory ITP elephant.
Blood Sep, 2016 | Pubmed ID: 27658695
Centralizing care of cancer-associated thromboembolism: The Cleveland Clinic experience.
Thrombosis research Nov, 2016 | Pubmed ID: 27721140
In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice.
Journal of thrombosis and haemostasis : JTH Feb, 2017 | Pubmed ID: 27925685
Post-traumatic stress disorder and depression in survivors of thrombotic thrombocytopenic purpura.
Thrombosis research Mar, 2017 | Pubmed ID: 28113083
Predicting risk of venous thromboembolism in hospitalized cancer patients: Utility of a risk assessment tool.
American journal of hematology Jun, 2017 | Pubmed ID: 28240823
Depression and post-traumatic stress disorder in individuals with hereditary hemorrhagic telangiectasia: A cross-sectional survey.
Thrombosis research May, 2017 | Pubmed ID: 28314138
Clinical outcomes in a cohort of patients with heparin-induced thrombocytopenia.
American journal of hematology Aug, 2017 | Pubmed ID: 28388835
Extracellular Vesicles in the Antiphospholipid Syndrome.
Seminars in thrombosis and hemostasis Jul, 2018 | Pubmed ID: 28476065
Clinical Risk Assessment in the Antiphospholipid Syndrome: Current Landscape and Emerging Biomarkers.
Current rheumatology reports Jul, 2017 | Pubmed ID: 28711993
Diagnosis and management of the antiphospholipid syndrome.
Blood reviews Nov, 2017 | Pubmed ID: 28784423
CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors.
The Journal of experimental medicine Sep, 2017 | Pubmed ID: 28838952
Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis.
American journal of physiology. Lung cellular and molecular physiology Mar, 2018 | Pubmed ID: 29122754
Preoperative Anemia in Cardiac Operation: Does Hemoglobin Tell the Whole Story?
The Annals of thoracic surgery Jan, 2018 | Pubmed ID: 29128046
Splenectomy for immune thrombocytopenia: down but not out.
Blood Mar, 2018 | Pubmed ID: 29295846
Novel Mechanism of Cancer Thrombosis Induced by Microvesicles.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2018 | Pubmed ID: 29563113
Current practice patterns and patient persistence with anticoagulant treatments for cancer-associated thrombosis.
Research and practice in thrombosis and haemostasis Jul, 2017 | Pubmed ID: 30046670
Effects of anti-β2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity.
Research and practice in thrombosis and haemostasis Apr, 2018 | Pubmed ID: 30046742
Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo.
Arteriosclerosis, thrombosis, and vascular biology Aug, 2018 | Pubmed ID: 30354195
Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model.
American journal of physiology. Lung cellular and molecular physiology Jan, 2019 | Pubmed ID: 30358441
Duration of anticoagulant therapy and VTE recurrence in patients with cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Oct, 2019 | Pubmed ID: 30734088
Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
Journal of thrombosis and haemostasis : JTH May, 2019 | Pubmed ID: 30801944
Complement in the Pathophysiology of the Antiphospholipid Syndrome.
Frontiers in immunology , 2019 | Pubmed ID: 30923524
Bleeding incidence and risk factors among cancer patients treated with anticoagulation.
American journal of hematology Jul, 2019 | Pubmed ID: 31006890
Implementation of an electronic medical record tool for early detection of deep vein thrombosis in the ambulatory oncology setting.
Research and practice in thrombosis and haemostasis Apr, 2019 | Pubmed ID: 31011706
Healthcare resource utilization and costs associated with venous thromboembolism in cancer patients treated with anticoagulants.
Journal of medical economics Nov, 2019 | Pubmed ID: 31106638
A non-circulating pool of factor XI associated with glycosaminoglycans in mice.
Journal of thrombosis and haemostasis : JTH Sep, 2019 | Pubmed ID: 31125187
Prognostic Value of Preoperative Red Cell Distribution Width: Fine-Tuning by Mean Corpuscular Volume.
The Annals of thoracic surgery Dec, 2019 | Pubmed ID: 31199898
American Society of Hematology 2019 guidelines for immune thrombocytopenia.
Blood advances Dec, 2019 | Pubmed ID: 31794604
Clinical outcomes of isolated distal deep vein thrombosis versus proximal venous thromboembolism in cancer patients: The Cleveland Clinic experience.
Journal of thrombosis and haemostasis : JTH Mar, 2020 | Pubmed ID: 31808607
Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.
Blood Jan, 2020 | Pubmed ID: 31812994
Healthcare resource utilization and costs associated with venous thromboembolism recurrence in patients with cancer.
Journal of medical economics Apr, 2020 | Pubmed ID: 31818164
Editorial: Proceedings of KININ2018CLE, Cleveland, Ohio, June 18-20, 2018: A Compendium of the Presentations.
Frontiers in medicine , 2019 | Pubmed ID: 31824955
Outcomes of Cardiovascular Surgery Utilizing Heparin versus Direct Thrombin Inhibitors in Cardiopulmonary Bypass in Patients with Previously Diagnosed HIT.
Thrombosis and haemostasis Feb, 2020 | Pubmed ID: 31887779
RNA expression and risk of venous thromboembolism in lung cancer.
Research and practice in thrombosis and haemostasis Jan, 2020 | Pubmed ID: 31989093
"HIT"ing back against NETs.
Blood Mar, 2020 | Pubmed ID: 32135015
FcRn augments induction of tissue factor activity by IgG-containing immune complexes.
Blood Jun, 2020 | Pubmed ID: 32187355
Report of a 'consensus' on the lines of therapy for primary immune thrombocytopenia in adults, promoted by the Italian Gruppo di Studio delle Piastrine.
Platelets May, 2020 | Pubmed ID: 32314933
The J-elongated conformation of β-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
The Journal of biological chemistry Jul, 2020 | Pubmed ID: 32518155
Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.
Blood Oct, 2020 | Pubmed ID: 32559765
Mechanisms and biomarkers of cancer-associated thrombosis.
Translational research : the journal of laboratory and clinical medicine Nov, 2020 | Pubmed ID: 32645431
SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy.
EBioMedicine Aug, 2020 | Pubmed ID: 32771682
Risk of thromboembolism in patients with ALK- and EGFR-mutant lung cancer: A cohort study.
Journal of thrombosis and haemostasis : JTH Mar, 2021 | Pubmed ID: 33314597
SARS-CoV-2 Receptors are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in COVID-19 Patients.
Research square Dec, 2020 | Pubmed ID: 33398263
Incidence of thromboembolism in patients with melanoma on immune checkpoint inhibitor therapy and its adverse association with survival.
Journal for immunotherapy of cancer Jan, 2021 | Pubmed ID: 33436486
Tapering thrombopoietin receptor agonists in primary immune thrombocytopenia: Expert consensus based on the RAND/UCLA modified Delphi panel method.
Research and practice in thrombosis and haemostasis Jan, 2021 | Pubmed ID: 33537531
Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure.
Blood Jul, 2021 | Pubmed ID: 33827130
A novel "vascular" thrombophilia.
Blood Apr, 2021 | Pubmed ID: 33885713
Efficacy and Safety of Avatrombopag in Patients with Chronic Immune Thrombocytopenia: A Systematic Literature Review and Network Meta-Analysis.
Advances in therapy Jun, 2021 | Pubmed ID: 33934279
Thrombotic thrombocytopenia due to SARS-CoV-2 vaccination.
Cleveland Clinic journal of medicine May, 2021 | Pubmed ID: 33958344
Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19.
Vascular medicine (London, England) Dec, 2021 | Pubmed ID: 34010070
Increased Incidence of Venous Thromboembolism with Cancer Immunotherapy.
Med (New York, N.Y.) Apr, 2021 | Pubmed ID: 34036293
Stress Granule-Mediated Oxidized RNA Decay in P-Body: Hypothetical Role of ADAR1, Tudor-SN, and STAU1.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34150849
Sclerotherapy Versus Cautery/Laser Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia.
The Laryngoscope May, 2022 | Pubmed ID: 34160081
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia.
Angiogenesis Feb, 2022 | Pubmed ID: 34292451
Polyphosphate expression by cancer cell extracellular vesicles mediates binding of factor XII and contact activation.
Blood advances Nov, 2021 | Pubmed ID: 34597365
Biomarker signatures in cancer patients with and without venous thromboembolism events: a substudy of CASSINI.
Blood advances Feb, 2022 | Pubmed ID: 34807979
Eculizumab for refractory thrombosis in antiphospholipid syndrome.
Blood advances Feb, 2022 | Pubmed ID: 35051999
Race, rituximab, and relapse in TTP.
Blood Sep, 2022 | Pubmed ID: 35797471
Development and performance of a hereditary hemorrhagic telangiectasia-specific quality-of-life instrument.
Blood advances Jul, 2022 | Pubmed ID: 35877137
Old is new again: emergence of thromboembolic complications in cancer patients on immunotherapy.
Thrombosis research May, 2022 | Pubmed ID: 36061419
Emerging Therapies in Antiphospholipid Syndrome.
Transfusion medicine reviews Oct, 2022 | Pubmed ID: 36272841
Anti-HK antibody inhibits the plasma contact system by blocking prekallikrein and factor XI activation in vivo.
Blood advances Apr, 2023 | Pubmed ID: 36409609
C1 inhibitor deficiency enhances contact pathway-mediated activation of coagulation and venous thrombosis.
Blood May, 2023 | Pubmed ID: 36701760
Transcriptome analysis suggests a central role for complement and C5aR1 in neutrophil activation in APS.
Thrombosis research Oct, 2023 | Pubmed ID: 37660437
Factor XII promotes the thromboinflammatory response in a rat model of venoarterial extracorporeal membrane oxygenation.
The Journal of thoracic and cardiovascular surgery Aug, 2024 | Pubmed ID: 37683721
High molecular weight kininogen interactions with the homologs prekallikrein and factor XI: importance to surface-induced coagulation.
Journal of thrombosis and haemostasis : JTH Jan, 2024 | Pubmed ID: 37813198
How to diagnose and manage antiphospholipid syndrome.
Hematology. American Society of Hematology. Education Program Dec, 2023 | Pubmed ID: 38066904
A descriptive analysis of fatal outcomes in immune thrombotic thrombocytopenic purpura in the USTMA TTP Registry.
Blood advances Feb, 2024 | Pubmed ID: 38100454
Dysregulated platelet function in patients with postacute sequelae of COVID-19.
Vascular medicine (London, England) Apr, 2024 | Pubmed ID: 38334067
The 2022 review of the 2019 American Society of Hematology guidelines on immune thrombocytopenia.
Blood advances Jul, 2024 | Pubmed ID: 38608258
A machine learning approach to predict mortality due to immune-mediated thrombotic thrombocytopenic purpura.
Research and practice in thrombosis and haemostasis Mar, 2024 | Pubmed ID: 38651093
A "backup plan" for ADAMTS13 deficiency in TTP.
Blood May, 2024 | Pubmed ID: 38753355
Catastrophic antiphospholipid syndrome: challenging case and importance of multidisciplinary evaluation and management.
Clinical case reports Jun, 2024 | Pubmed ID: 38868115
Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia.
The New England journal of medicine Sep, 2024 | Pubmed ID: 39292928
Complement biosensors identify a classical pathway stimulus in complement-mediated thrombotic microangiopathy.
Blood Dec, 2024 | Pubmed ID: 39357054
Relapse-free survival is progressively shortened in a subset of Black patients with immune-mediated TTP treated in the rituximab era.
Blood advances Jan, 2025 | Pubmed ID: 39626301
Pomalidomide in Hereditary Hemorrhagic Telangiectasia. Reply.
The New England journal of medicine Dec, 2024 | Pubmed ID: 39665668
Protection of β2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation.
Blood May, 2025 | Pubmed ID: 39869832
Idiopathic multicentric Castleman disease - TAFRO results in high levels of mTOR activator SVEP1, tissue factor, and endotheliopathy.
Blood vessels, thrombosis & hemostasis Jun, 2024 | Pubmed ID: 40191177
Genetic and Epigenetic Dysregulation of CR1 is Associated with Catastrophic Antiphospholipid Syndrome (CAPS).
medRxiv : the preprint server for health sciences May, 2025 | Pubmed ID: 40385421
版权所属 © 2025 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。