State Key Laboratory of Respiratory Diseases,
National Center for Respiratory Medicine,
Guangdong Key Laboratory of Vascular Diseases,
National Clinical Research Center for Respiratory Diseases,
Guangzhou Institute of Respiratory Health,
State Key Laboratory of Respiratory Diseases, National Center for Respiratory Medicine, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health
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Promising therapeutic effects of sodium tanshinone IIA sulfonate towards pulmonary arterial hypertension in patients.
Journal of thoracic disease Apr, 2013 | Pubmed ID: 23585945
Remodeling of rat pulmonary artery induced by chronic smoking exposure.
Journal of thoracic disease Jun, 2014 | Pubmed ID: 24977008
Chronic hypoxia increases TRPC6 expression and basal intracellular Ca2+ concentration in rat distal pulmonary venous smooth muscle.
PloS one , 2014 | Pubmed ID: 25365342
Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry.
Journal of molecular medicine (Berlin, Germany) Mar, 2015 | Pubmed ID: 25391250
Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis.
American journal of physiology. Cell physiology Jul, 2016 | Pubmed ID: 27194472
Bortezomib alleviates experimental pulmonary hypertension by regulating intracellular calcium homeostasis in PASMCs.
American journal of physiology. Cell physiology Sep, 2016 | Pubmed ID: 27413173
Comparison and evaluation of two different methods to establish the cigarette smoke exposure mouse model of COPD.
Scientific reports Nov, 2017 | Pubmed ID: 29133824
Pharmacological activation of PPARγ inhibits hypoxia-induced proliferation through a caveolin-1-targeted and -dependent mechanism in PASMCs.
American journal of physiology. Cell physiology Apr, 2018 | Pubmed ID: 29351409
Establishment and evaluation of chronic obstructive pulmonary disease model by chronic exposure to motor vehicle exhaust combined with lipopolysaccharide instillation.
Experimental physiology Nov, 2018 | Pubmed ID: 30070749
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology Jan, 2019 | Pubmed ID: 30358436
Transplantation of Mesenchymal Stem Cells Attenuates Pulmonary Hypertension by Normalizing the Endothelial-to-Mesenchymal Transition.
American journal of respiratory cell and molecular biology Jan, 2020 | Pubmed ID: 31211918
Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study.
Trials Dec, 2019 | Pubmed ID: 31842950
Structural and functional definition of the pulmonary vein system in a chronic hypoxia-induced pulmonary hypertension rat model.
American journal of physiology. Cell physiology Mar, 2020 | Pubmed ID: 31940248
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
British journal of pharmacology Jun, 2020 | Pubmed ID: 31976548
Correction to: Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study.
Trials Mar, 2020 | Pubmed ID: 32228673
A novel rat model of pulmonary hypertension induced by mono treatment with SU5416.
Hypertension research : official journal of the Japanese Society of Hypertension Aug, 2020 | Pubmed ID: 32472112
Altered Airway Microbiota Composition in Patients With Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) Nov, 2020 | Pubmed ID: 32921193
PDGF/MEK/ERK axis represses Ca clearance via decreasing the abundance of plasma membrane Ca pump PMCA4 in pulmonary arterial smooth muscle cells.
American journal of physiology. Cell physiology Jan, 2021 | Pubmed ID: 32966125
Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats.
British journal of pharmacology Jan, 2021 | Pubmed ID: 33080042
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats.
British journal of pharmacology Jan, 2021 | Pubmed ID: 33140842
Response to Michiel Alexander de Raaf et al.
Hypertension research : official journal of the Japanese Society of Hypertension Apr, 2021 | Pubmed ID: 33442030
Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arterial Hypertension Patients.
Hypertension (Dallas, Tex. : 1979) Jun, 2021 | Pubmed ID: 33813851
The causality between CFTR and pulmonary hypertension: insights from Mendelian randomization studies.
Hypertension research : official journal of the Japanese Society of Hypertension Sep, 2021 | Pubmed ID: 34155362
Bufei huoxue capsules in the management of convalescent COVID-19 infection: study protocol for a multicenter, double-blind, and randomized controlled trial.
Pulmonary circulation , 2021 | Pubmed ID: 34394913
Established pulmonary hypertension in rats was reversed by a combination of a HIF-2α antagonist and a p53 agonist.
British journal of pharmacology Mar, 2022 | Pubmed ID: 34599843
Resolvin E1 Attenuates Pulmonary Hypertension by Suppressing Wnt7a/β-Catenin Signaling.
Hypertension (Dallas, Tex. : 1979) Dec, 2021 | Pubmed ID: 34689593
Efficacy and safety of Bufei Huoxue capsules in the management of convalescent patients with COVID-19 infection: A multicentre, double-blind, and randomised controlled trial.
Journal of ethnopharmacology Feb, 2022 | Pubmed ID: 34763045
Natural ingredients from Chinese materia medica for pulmonary hypertension.
Chinese journal of natural medicines Nov, 2021 | Pubmed ID: 34844719
LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca] in Pulmonary Arterial Smooth Muscle Cells.
American journal of respiratory cell and molecular biology May, 2022 | Pubmed ID: 35148256
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells.
Biochemical pharmacology May, 2022 | Pubmed ID: 35276216
Visibility, wind speed, and dew point temperature are important factors in SARS-CoV-2 transmissibility.
Pulmonary circulation Apr, 2022 | Pubmed ID: 35514785
Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension.
Thrombosis research Oct, 2022 | Pubmed ID: 35988445
The impact of the COVID-19 pandemic on the care of pulmonary hypertension patients outside the Hubei province in China.
Pulmonary circulation Jul, 2022 | Pubmed ID: 36186716
Microbiome and metabolome dysbiosis of the gut-lung axis in pulmonary hypertension.
Microbiological research Dec, 2022 | Pubmed ID: 36202007
Respiratory Microbiome Profile of Pediatric Pulmonary Hypertension Patients Associated With Congenital Heart Disease.
Hypertension (Dallas, Tex. : 1979) Jan, 2023 | Pubmed ID: 36353996
Prediction and prognosis of adverse maternal and foetal/neonatal outcomes in pulmonary hypertension: an observational study and nomogram construction.
Respiratory research Nov, 2022 | Pubmed ID: 36376948
Editorial: Calcium and pulmonary hypertension.
Frontiers in physiology , 2022 | Pubmed ID: 36407003
Correction to: Prediction and prognosis of adverse maternal and foetal/neonatal outcomes in pulmonary hypertension: an observational study and nomogram construction.
Respiratory research Jan, 2023 | Pubmed ID: 36611163
Piezo1, a novel therapeutic target to treat pulmonary arterial hypertension.
Frontiers in physiology , 2023 | Pubmed ID: 36776977
Airway delivery of Streptococcus salivarius is sufficient to induce experimental pulmonary hypertension in rats.
British journal of pharmacology Aug, 2023 | Pubmed ID: 36869838
Bufei huoxue capsule alleviates bleomycin-induced pulmonary fibrosis in mice via TGF-β1/Smad2/3 signaling.
Journal of ethnopharmacology Nov, 2023 | Pubmed ID: 37277082
Echocardiographic evaluation of right heart failure which might be associated with DNA damage response in SU5416-hypoxia induced pulmonary hypertension rat model.
Respiratory research Aug, 2023 | Pubmed ID: 37592245
Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation.
Cardiovascular research Mar, 2024 | Pubmed ID: 38198357
Non-invasive estimation of pulmonary hypertension and clinical deterioration risk in pediatric congenital heart disease: Development and validation of predictive tools.
Chinese medical journal Jun, 2024 | Pubmed ID: 38595105
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension.
Clinical and translational medicine Jun, 2024 | Pubmed ID: 38861300
Integrated approach of network pharmacology, molecular docking, and clinical observations in evaluating the efficacy and safety of Bufei Huoxue capsules for pulmonary hypertension associated with chronic obstructive pulmonary disease.
Pulmonary circulation Jul, 2024 | Pubmed ID: 39035784
Nephrectomy and high-salt diet inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in rats.
Respiratory research Jul, 2024 | Pubmed ID: 39080603
Estrogen Oppositely Regulates Pulmonary Hypertension via METTL3/PFKFB3 under Normoxia and Hypoxia.
American journal of respiratory cell and molecular biology Mar, 2025 | Pubmed ID: 39265182
The role of Keap1-Nrf2 signaling pathway in the treatment of respiratory diseases and the research progress on targeted drugs.
Heliyon Sep, 2024 | Pubmed ID: 39309822
A study on the genetic comorbidity between autoimmune diseases and pulmonary hypertension: an observational study and POST-GWAS analysis.
International journal of medical sciences , 2025 | Pubmed ID: 40084256
Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension.
BMC pulmonary medicine Apr, 2025 | Pubmed ID: 40169967
A Subgroup Reanalysis of the Efficacy of Bufei Huoxue Capsules in Patients With "Long-Covid-19".
Pulmonary circulation Apr, 2025 | Pubmed ID: 40291435
Qian Jiang*,1,
Dongmei Wen*,1,
Fang Peng*,2,
Wei Hong3,
Xin Fu3,
Yuanhui Xiong1,
Chongyuan Ren1,
Xuanyi Li1,
Dansha Zhou1,4,
Jian Wang1,4,
Yuqin Chen1
1State Key Laboratory of Respiratory Diseases, National Center for Respiratory Medicine, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University,
2Department of Critical Care Medicine, The Third Affiliated Hospital of Guangzhou Medical University,
3GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University,
4Guangzhou laboratory, Guangzhou International Bio Island
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