Ping Xu

A novel whole-cell biocatalyst with NAD+ regeneration for production of chiral chemicals.

Effect of domperidone therapy on nocturnal dyspeptic symptoms of functional dyspepsia patients.

Synthesis and preliminary evaluation of peptidomimetic inhibitors of human beta-secretase.

Facile fabrication of homogeneous 3D silver nanostructures on gold-supported polyaniline membranes as promising SERS substrates.

Ubiquitin chain elongation enzyme Ufd2 regulates a subset of Doa10 substrates.

[Health status and affecting factors of late-preterm infants].

Results of a randomized phase I dose-finding trial of several doses of isoflavones in men with localized prostate cancer: administration prior to radical prostatectomy.

Functional promoter -1271G>C variant of HSPB1 predicts lung cancer risk and survival.

Impact of metronomic UFT/cyclophosphamide chemotherapy and antiangiogenic drug assessed in a new preclinical model of locally advanced orthotopic hepatocellular carcinoma.

Vitamin B3, the nicotinamide adenine dinucleotides and aging.

Experimental realization of a controlled-NOT gate with four-photon six-qubit cluster states.

The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5.

Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer.

Kinetics of D-lactic acid production by Sporolactobacillus sp. strain CASD using repeated batch fermentation.

Production of 2,3-butanediol from corncob molasses, a waste by-product in xylitol production.

Repeated open fermentative production of optically pure L-lactic acid using a thermophilic Bacillus sp. strain.

Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin.

Contrast-enhanced ultrasonographic findings of different histopathologic types of breast cancer.

Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran.

Metabolic versatility of halotolerant and alkaliphilic strains of Halomonas isolated from alkaline black liquor.

The Prp19 WD40 domain contains a conserved protein interaction region essential for its function.

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

Production of L-lactic acid by a thermophilic Bacillus mutant using sodium hydroxide as neutralizing agent.

Biotechnological production and applications of N-acetyl-D-neuraminic acid: current state and perspectives.

Cloning, expression, purification, and activity assay of proteins related to D-lactic acid formation in Lactobacillus rhamnosus.

Validated LC-MS (ESI) assay for the simultaneous determination of amitriptyline and its metabolite nortriptyline in rat plasma: application to a pharmacokinetic comparison.

Characterization and biotechnological potential of petroleum-degrading bacteria isolated from oil-contaminated soils.

Laparoscopic extraperitoneal uterine suspension to anterior abdominal wall bilaterally using synthetic mesh to treat uterovaginal prolapse.

Efficient production of l-lactic acid from corncob molasses, a waste by-product in xylitol production, by a newly isolated xylose utilizing Bacillus sp. strain.

Efficient production of l-lactic acid from cassava powder by Lactobacillus rhamnosus.

[Accuracy of perioperative cardiac preload monitoring by global end-diastolic volume and intrathoracic blood volume in orthotopic liver transplantation].

Pooled protein immunization for identification of cell surface antigens in Streptococcus sanguinis.

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.

Prognostic performance of metabolic indexes in predicting onset of type 1 diabetes.

Field-assisted synthesis of SERS-active silver nanoparticles using conducting polymers.

Peripartum serum leptin and soluble leptin receptor levels in women with gestational diabetes.

Pioglitazone: a promising therapeutic tool in sodium taurocholate-induced severe acute pancreatitis.

Identification of hydrogen peroxide production-related genes in Streptococcus sanguinis and their functional relationship with pyruvate oxidase.

A novel conditionally replicating "armed" adenovirus selectively targeting gastrointestinal tumors with aberrant wnt signaling.

Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism.

Zernike apodized photon sieves for high-resolution phase-contrast x-ray microscopy.

Highly efficient production of D-lactate by Sporolactobacillus sp. CASD with simultaneous enzymatic hydrolysis of peanut meal.

NSSR1 is regulated by testosterone in the mouse uterus and extensively expressed in endometrial carcinoma.

Development of a resistance-like phenotype to sorafenib by human hepatocellular carcinoma cells is reversible and can be delayed by metronomic UFT chemotherapy.

Antithrombotic effect of grape seed proanthocyanidins extract in a rat model of deep vein thrombosis.

Frequent down-regulation of hABH2 in gastric cancer and its involvement in growth of cancer cells.

ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.

Mechanism-based affinity capture of sirtuins.

An alternative flat scanner and micropositioning method for scanning probe microscope.

Diverse polyubiquitin chains accumulate following 26S proteasomal dysfunction in mammalian neurones.

[Bacterial promoter recognition and application].

[Strategies for regulating multiple genes in microbial cell factories].

Degradation of n-alkanes and polycyclic aromatic hydrocarbons in petroleum by a newly isolated Pseudomonas aeruginosa DQ8.

Mouse models of advanced spontaneous metastasis for experimental therapeutics.

Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease.

Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase.

Rare earth metal bis(amide) complexes bearing amidinate ancillary ligands: synthesis, characterization, and performance as catalyst precursors for cis-1,4 selective polymerization of isoprene.

JNK regulates FoxO-dependent autophagy in neurons.

Ubiquitinated proteome: ready for global?

Trypanosoma cruzi infection induces a global host cell response in cardiomyocytes.

Racial ethnic differences in rates and determinants of deceased donor kidney transplantation.

Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog.

In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes.

HuD regulates the cpg15 expression via the 3'-UTR and AU-rich element.

Mechanistic study of silver nanoparticle formation on conducting polymer surfaces.

Biodiesel production in packed-bed reactors using lipase-nanoparticle biocomposite.

Production of N-acetyl-D-neuraminic acid by use of an efficient spore surface display system.

Nonlinear generation of a neat semi-Gaussian laser beam with a transversely varying periodically-poled LiTaO3 crystal.

Novel N-chloroheterocyclic antimicrobials.

Relationship of body size and mortality among US Asians and Pacific Islanders on dialysis.

Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting DNMT1 through suppression of total DNA methyltransferase activity.

Advances and prospects: biotechnologically improving crop water use efficiency.

Prokaryotic expression and identification of 3-1E gene of merozoite surface antigen of Eimeria acervulina.

Effect of electro-acupuncture intervention on cognition attention bias in heroin addiction abstinence-a dot-probe-based event-related potential study.

Efficient conversion of phenylpyruvic acid to phenyllactic acid by using whole cells of Bacillus coagulans SDM.

Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines.

Recent advances in biotechnological production of 2-phenylethanol.

Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.

Natural Orifice Translumenal Endoscopic Surgery (NOTES): patients' perceptions and attitudes.

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.

How to measure secondhand smoke exposure in a pediatric clinic setting.

Development of a sandwich ELISA for evaluating soluble PD-L1 (CD274) in human sera of different ages as well as supernatants of PD-L1+ cell lines.

Metronomic oral topotecan with pazopanib is an active antiangiogenic regimen in mouse models of aggressive pediatric solid tumor.

Structural basis for the recognition of Asef by adenomatous polyposis coli.

Chemoenzymatic synthesis of N-acetyl-D-neuraminic acid from N-acetyl-D-glucosamine by using the spore surface-displayed N-acetyl-D-neuraminic acid aldolase.

Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial.

Role of signal transducer and activator of transcription-3 in up-regulation of GFAP after epilepsy.

Biotechnological routes based on lactic acid production from biomass.

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.

Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.

Novel organic solvent-responsive expression vectors for biocatalysis: application for development of an organic solvent-tolerant biodesulfurizing strain.

Sequential chemical deposition of metal alloy jellyfish using polyaniline: redox chemistry at the metal-polymer interface.

Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity.

Enzyme-nanoporous gold biocomposite: excellent biocatalyst with improved biocatalytic performance and stability.

Complete genome sequence of the nicotine-degrading Pseudomonas putida strain S16.

Physicochemical properties, in vitro antioxidant activities and inhibitory potential against α-glucosidase of polysaccharides from Ampelopsis grossedentata leaves and stems.

Identification and immunological characterization of three potential vaccinogens against Cryptosporidium species.

Metabolic characterization and genes for the conversion of biphenyl in Dyella ginsengisoli LA-4.

Genetic analysis of D-xylose metabolism by endophytic yeast strains of Rhodotorula graminis and Rhodotorula mucilaginosa.

Biocatalytic production of (2S,3S)-2,3-butanediol from diacetyl using whole cells of engineered Escherichia coli.

Production of (2S,3S)-2,3-butanediol and (3S)-acetoin from glucose using resting cells of Klebsiella pneumonia and Bacillus subtilis.

A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida.

Draft genome sequence of Sporolactobacillus inulinus strain CASD, an efficient D-lactic acid-producing bacterium with high-concentration lactate tolerance capability.

Evening versus morning dosing regimen drug therapy for hypertension.

Regional differences in dialysis care and mortality among American Indians and Alaska Natives.

Tunable fluorescent pH sensor based on water-soluble perylene tetracarboxylic acid/Fe(3+).

Loss of AtPDR11, a plasma membrane-localized ABC transporter, confers paraquat tolerance in Arabidopsis thaliana.

Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations.

Genome sequence of the thermophilic strain Bacillus coagulans XZL4, an efficient pentose-utilizing producer of chemicals.

Genome sequence of Bacillus pumilus S-1, an efficient isoeugenol-utilizing producer for natural vanillin.

Genome sequence of Sphingobium yanoikuyae XLDN2-5, an efficient carbazole-degrading strain.

Genome sequence of Rhodococcus erythropolis XP, a biodesulfurizing bacterium with industrial potential.

Genome sequence of Pseudomonas putida strain B6-2, a superdegrader of polycyclic aromatic hydrocarbons and dioxin-like compounds.

Supercritical Carbon Dioxide Extraction of Bioactive Compounds from Ampelopsis grossedentata Stems: Process Optimization and Antioxidant Activity.

The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.

Molecular imaging of breast tumors using a near-infrared fluorescently labeled clusterin binding peptide.

Genome sequence of Pseudomonas putida Idaho, a unique organic-solvent-tolerant bacterium.

Genome sequence of Lactobacillus rhamnosus strain CASL, an efficient L-lactic acid producer from cheap substrate cassava.

Genome sequence of Sphingomonas elodea ATCC 31461, a highly productive industrial strain of gellan gum.

Efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans.

Subarachnoid hemorrhage associated with epidemic hemorrhagic fever: a rare case report.

[The association of non-specific chronic inflammation with dendritic cells in a rat model of chronic obstructive pulmonary disease].

Fatty Acid Composition and Antioxidant Activity of Tea (Camellia sinensis L.) Seed Oil Extracted by Optimized Supercritical Carbon Dioxide.

Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesis.

Dendrimer-modified gold nanorods as efficient controlled gene delivery system under near-infrared light irradiation.

HIV Screening and Awareness Survey for Pregnant Women in a Remote Area in Xinjiang Uyghur Autonomous Region of China.

Roles for Endothelin Receptor B and BCL2A1 in Spontaneous CNS Metastasis of Melanoma.

Aortic leaflet replacement with fresh autologous pericardium: at 17-year follow-up.

Hepatoprotective effects of select water-soluble PARP inhibitors in a carbon tetrachloride model.

Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer.

Use and helpfulness of self-administered stress management therapy in patients undergoing cancer chemotherapy in community clinical settings.

Genome sequence of Pseudomonas stutzeri SDM-LAC, a typical strain for studying the molecular mechanism of lactate utilization.

Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol.

Serum decoy receptor 3, a potential new biomarker for sepsis.

Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1.

Effect of a CNS-Sensitive Anticholinesterase Methane Sulfonyl Fluoride on Hippocampal Acetylcholine Release in Freely Moving Rats.

Radioprotective effects of troxerutin against gamma irradiation in V79 cells and mice.

Genome Sequence of Pseudomonas chlororaphis GP72, a Root-Colonizing Biocontrol Strain.

Efficient bioconversion of l-threonine to 2-oxobutyrate using whole cells of Pseudomonas stutzeri SDM.

Relative catalytic efficiency of ldhL- and ldhD-encoded products is crucial for optical purity of lactic acid produced by lactobacillus strains.

Validated LC-MS/MS assay for the quantitative determination of clematichinenoside AR in rat plasma and its application to a pharmacokinetic study.

No decrease in susceptibility to NVC-422 in multiple-passage studies with methicillin-resistant Staphylococcus aureus, S. aureus, Pseudomonas aeruginosa, and Escherichia coli.

Genome-wide essential gene identification in Streptococcus sanguinis.

One-pot bio-synthesis: N-acetyl-d-neuraminic acid production by a powerful engineered whole-cell catalyst.

[Application of regionalized critical neonatal emergency transport system].

The discovery of novel β-secretase inhibitors: pharmacophore modeling, virtual screening, and docking studies.

Lactate utilization is regulated by the FadR-type regulator LldR in Pseudomonas aeruginosa.

Enhancement of rAAV2-mediated transgene expression in retina cells in vitro and in vivo by coadministration of low-dose chemotherapeutic drugs.

Identification of nicotine biotransformation intermediates by Agrobacterium tumefaciens strain S33 suggests a novel nicotine degradation pathway.

Efficient utilization of hemicellulose hydrolysate for propionic acid production using Propionibacterium acidipropionici.

Effects of double filtration plasmapheresis, leflunomide, and methotrexate on inflammatory changes found through magnetic resonance imaging in early rheumatoid arthritis.

Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation.

Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models.

Highly sensitive surface-enhanced Raman spectroscopy (SERS) platforms based on silver nanostructures fabricated on polyaniline membrane surfaces.

Effect of acculturation and distance from cardiac center on congenital heart disease mortality.

Radioprotective effects of troxerutin against gamma irradiation in mice liver.

NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM.

Lack of association between TNF-α gene promoter polymorphisms and pancreatitis: a meta-analysis.

[Study of radiographic method of increasing vertical angle for identifying double root in maxillary premolar with cone-beam CT].

A Preliminary Investigation on NSCLP Plasma and Urine in Guizhou Province in CHINA Using NMR-Based Metabonomics.

PepDistiller: A quality control tool to improve the sensitivity and accuracy of peptide identifications in shotgun proteomics.

[Phenotype analysis and mutant gene location of ventral yellow mouse (VY(Slac))].

Genome sequence of Sphingomonas wittichii DP58, the first reported phenazine-1-carboxylic acid-degrading strain.

Genome sequence of a novel nicotine-degrading strain, Pseudomonas geniculata N1.

Application of case classification in healthcare quality assessment in China.

[Effect of 18alpha-glycyrrhizic acid and 18beta-glycyrrhizic acid on P-gp function and expression in Caco-2 cells].

Carotenoids play a positive role in the degradation of heterocycles by Sphingobium yanoikuyae.

Genetic loci controlling lethal cell death in tomato caused by viral satellite RNA infection.

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.

[Effect of electroacupuncture on expression of caspase-3 and phosphorylated Akt proteins in the skeleton muscle in diabetic mice].

SpxA1 involved in hydrogen peroxide production, stress tolerance and endocarditis virulence in Streptococcus sanguinis.

Protective effect of an extract of Guipi Pill against radiation-induced damage in mice.

Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high-risk population: receiver operating characteristic analysis.

Efficient 2,3-butanediol production from cassava powder by a crop-biomass-utilizer, Enterobacter cloacae subsp. dissolvens SDM.

Efficient production of pyruvate from DL-lactate by the lactate-utilizing strain Pseudomonas stutzeri SDM.

Metabolomic analysis of biochemical changes in the plasma and urine of first-episode neuroleptic-naïve schizophrenia patients after treatment with risperidone.

Synthesis of electromagnetic functionalized Fe3O4 microspheres/polyaniline composites by two-step oxidative polymerization.

Treatment of idiopathic pulmonary fibrosis with losartan: a pilot project.

Genome sequences of two thermophilic Bacillus licheniformis strains, efficient producers of platform chemical 2,3-butanediol.

Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications.

Genome sequence of Klebsiella pneumoniae LZ, a potential platform strain for 1,3-propanediol production.

Genome sequence of a novel indigo-producing strain, Pseudomonas monteilii QM.

Quantum teleportation and entanglement distribution over 100-kilometre free-space channels.

Synthesis, in vitro Biological Evaluation and Molecular Docking Studies of Benzimidamides as Potential BACE1 Inhibitors.

Genome sequence of the lactate-utilizing Pseudomonas aeruginosa strain XMG.

Genome sequence of Xanthomonas campestris JX, an industrially productive strain for Xanthan gum.

Improved microbial fuel cell performance by encapsulating microbial cells with a nickel-coated sponge.

Lack of effect of continuous glycyrrhizin administration on the pharmacokinetics of the P-glycoprotein substrate talinolol in healthy volunteers.

Genome Sequences of Pseudomonas luteola XLDN4-9 and Pseudomonas stutzeri XLDN-R, Two Efficient Carbazole-Degrading Strains.

Genome sequence of a nicotine-degrading strain of arthrobacter.

Genome Sequence of Pseudomonas putida S12, a Potential Platform Strain for Industrial Production of Valuable Chemicals.

Genome Sequence of the Welan Gum-Producing Strain Sphingomonas sp. ATCC 31555.

Oral administration of puerh tea polysaccharides lowers blood glucose levels and enhances antioxidant status in alloxan-induced diabetic mice.

Protein Profiling of Active Cysteine Cathepsins in Living Cells Using an Activity-Based Probe Containing a Cell-Penetrating Peptide.

Genome Sequence of the Thermophile Bacillus coagulans Hammer, the Type Strain of the Species.

Genome Sequence of Pseudomonas aeruginosa DQ8, an Efficient Degrader of n-Alkanes and Polycyclic Aromatic Hydrocarbons.

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition.

Rationally re-designed mutation of NAD-independent L-lactate dehydrogenase: high optical resolution of racemic mandelic acid by the engineered Escherichia coli.

Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection.

Studies on the bioactivity of aqueous extract of pu-erh tea and its fractions: in vitro antioxidant activity and α-glycosidase inhibitory property, and their effect on postprandial hyperglycemia in diabetic mice.

Pulp mill wastewater sediment reveals novel methanogenic and cellulolytic populations.

Fabrication of thorny Au nanostructures on polyaniline surfaces for sensitive surface-enhanced Raman spectroscopy.

Transcription elongation factor GreA has functional chaperone activity.

Qualitative and quantitative expression status of the human chromosome 20 genes in cancer tissues and the representative cell lines.

Proteome atlas of human chromosome 8 and its multiple 8p deficiencies in tumorigenesis of the stomach, colon, and liver.

CAPER: a chromosome-assembled human proteome browsER.

First proteomic exploration of protein-encoding genes on chromosome 1 in human liver, stomach, and colon.

Jerusalem artichoke powder: a useful material in producing high-optical-purity l-lactate using an efficient sugar-utilizing thermophilic Bacillus coagulans strain.

Characterization of a novel metagenome-derived 6-phospho-β-glucosidase from black liquor sediment.

ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance.

Broad-spectrum virucidal activity of (NVC-422) N,N-dichloro-2,2-dimethyltaurine against viral ocular pathogens in vitro.

Two-component system response regulators involved in virulence of Streptococcus pneumoniae TIGR4 in infective endocarditis.

Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.

Characterization of nuclear localization signals (NLSs) and function of NLSs and phosphorylation of serine residues in subcellular and subnuclear localization of transformer-2β (Tra2β).

Genome Sequence of Sphingomonas xenophaga QYY, an Anthraquinone-Degrading Strain.

Production of hydroxypyruvate from glycerate by a novel biotechnological route.

New constitutive vectors: useful genetic engineering tools for biocatalysis.

Evolutionary characterization of the pandemic H1N1/2009 influenza virus in humans based on non-structural genes.

A carbon-nanotube-supported graphene-rich non-precious metal oxygen reduction catalyst with enhanced performance durability.

Phylogeography and domestication of Chinese swamp buffalo.

Laser wavelength- and power-dependent plasmon-driven chemical reactions monitored using single particle surface enhanced Raman spectroscopy.

A prescribed chinese herbal medicine improves glucose profile and ameliorates oxidative stress in goto-kakisaki rats fed with high fat diet.

Production of (3S)-acetoin from diacetyl by using stereoselective NADPH-dependent carbonyl reductase and glucose dehydrogenase.

Efficient biocatalyst by encapsulating lipase into nanoporous gold.

A model of postsurgical advanced metastatic breast cancer more accurately replicates the clinical efficacy of antiangiogenic drugs.

Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation.

Genome Sequences of Two Morphologically Distinct and Thermophilic Bacillus coagulans Strains, H-1 and XZL9.

Substituted 3-Benzylcoumarins as Allosteric MEK1 Inhibitors: Design, Synthesis and Biological Evaluation as Antiviral Agents.

Prevalence of Blindness and Outcomes of Cataract Surgery in Hainan Province in South China.

Systematic research on the pre-treatment of peptides for quantitative proteomics using a C18 microcolumn.

Generation and Characterization of Two Novel Monoclonal Antibodies Produced Against Human TLT-2 Molecule.

A mechanistic physiologically based pharmacokinetic-enzyme turnover model involving both intestine and liver to predict CYP3A induction-mediated drug-drug interactions.