Department of Cardiothoracic Surgery,
Department of CT Surgery,
CT Surgery
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Myoblasts survive intracardiac transfer and divide further after transplantation.
The heart surgery forum , 2002 | Pubmed ID: 12538115
New technique for chest opening in mice: U-sternotomy.
Microsurgery , 2003 | Pubmed ID: 12833331
Successful resection of a symptomatic right ventricular lipoma.
The Annals of thoracic surgery Oct, 2003 | Pubmed ID: 14530040
Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model.
Transplantation Dec, 2003 | Pubmed ID: 14702537
The interaction between FK778 and tacrolimus in the prevention of rat cardiac allograft rejection is dose dependent.
Transplantation Feb, 2004 | Pubmed ID: 15084926
FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.
Transplantation Jul, 2004 | Pubmed ID: 15257041
FK778, a novel immunosuppressive agent, reduces early adhesion molecule up-regulation and prolongs cardiac allograft survival.
Transplant international : official journal of the European Society for Organ Transplantation Feb, 2005 | Pubmed ID: 15691275
The phytoestrogen biochaninA weakens acute cardiac allograft rejection without affecting the reproductive system.
Transplant immunology Oct, 2005 | Pubmed ID: 16223672
FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Nov, 2005 | Pubmed ID: 16297791
Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.
Transplant international : official journal of the European Society for Organ Transplantation Apr, 2006 | Pubmed ID: 16573547
Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Circulation Apr, 2006 | Pubmed ID: 16606792
The selective estrogen receptor-beta agonist biochanin A shows vasculoprotective effects without uterotrophic activity.
Menopause (New York, N.Y.) May-Jun, 2006 | Pubmed ID: 16735947
Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
Cardiology , 2007 | Pubmed ID: 17028423
FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Jan, 2007 | Pubmed ID: 17234520
Coincidence of aortic valve stenosis and regurgitation and multiple cardiac papillary fibroelastomas in a young male adult.
The Journal of thoracic and cardiovascular surgery Feb, 2007 | Pubmed ID: 17258602
Experimental orthotopic tracheal transplantation: The Stanford technique.
Microsurgery , 2007 | Pubmed ID: 17326196
Simplified protocol to isolate, purify, and culture expand mesenchymal stem cells.
Stem cells and development Feb, 2007 | Pubmed ID: 17348808
Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?
Transplant immunology Jun, 2007 | Pubmed ID: 17493528
Right atrial mass after primary repair of an atrial septal defect: thrombus masquerading as a myxoma.
The Annals of thoracic surgery Nov, 2007 | Pubmed ID: 17954102
Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2008 | Pubmed ID: 18272654
Failed induction of heme oxygenase 1 in endothelial cells exposed to the hemoglobin based oxygen carrier Oxyglobin.
Artificial cells, blood substitutes, and immobilization biotechnology , 2008 | Pubmed ID: 18293159
Introducing the first polymer-free leflunomide eluting stent.
Atherosclerosis Sep, 2008 | Pubmed ID: 18295768
Prevention and inhibition but not reversion of chronic allograft vasculopathy by FK778.
Transplantation Mar, 2008 | Pubmed ID: 18360270
Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.
Transplantation Mar, 2008 | Pubmed ID: 18360272
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation.
Stem cells and development Dec, 2008 | Pubmed ID: 18491958
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18728188
Comparison of different adult stem cell types for treatment of myocardial ischemia.
Circulation Sep, 2008 | Pubmed ID: 18824743
Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart.
Transplantation Mar, 2009 | Pubmed ID: 19295307
A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.
Transplantation Mar, 2009 | Pubmed ID: 19295308
Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.
Circulation Sep, 2009 | Pubmed ID: 19752375
Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Nov, 2009 | Pubmed ID: 19782602
Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation.
American journal of respiratory cell and molecular biology Oct, 2010 | Pubmed ID: 19880819
Non-volume-loaded heart provides a more relevant heterotopic transplantation model.
Transplant immunology May, 2010 | Pubmed ID: 20403439
Sustained inhibition of epsilon protein kinase C inhibits vascular restenosis after balloon injury and stenting.
Circulation Sep, 2010 | Pubmed ID: 20837910
Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells.
Cell transplantation , 2011 | Pubmed ID: 21054940
Prevention of transplant coronary artery disease by prenylation inhibitors.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Jul, 2011 | Pubmed ID: 21458297
Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo.
PloS one , 2011 | Pubmed ID: 21850255
Immunobiology of naïve and genetically modified HLA-class-I-knockdown human embryonic stem cells.
Journal of cell science Sep, 2011 | Pubmed ID: 21878509
Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.
Circulation Sep, 2011 | Pubmed ID: 21911816
Assessment of physiologic natural killer cell cytotoxicity in vitro.
Human immunology Nov, 2011 | Pubmed ID: 21924314
Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.
Circulation research Mar, 2012 | Pubmed ID: 22427341
Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.
Transplantation Oct, 2012 | Pubmed ID: 22971540
Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.
Circulation research Jan, 2013 | Pubmed ID: 23065358
The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease.
Transplantation Jan, 2013 | Pubmed ID: 23325003
Small animal models of experimental obliterative bronchiolitis.
American journal of respiratory cell and molecular biology Jun, 2013 | Pubmed ID: 23392572
Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue.
Stem cells and development Oct, 2013 | Pubmed ID: 23711207
The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy.
PloS one , 2013 | Pubmed ID: 24312257
Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.
Nature Apr, 2014 | Pubmed ID: 24747400
miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.
Nature communications Oct, 2014 | Pubmed ID: 25358394
SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.
Cell stem cell Jan, 2015 | Pubmed ID: 25465116
Erratum: miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.
Nature communications Feb, 2015 | Pubmed ID: 25716653
Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy.
The Journal of infectious diseases Oct, 2015 | Pubmed ID: 25805750
Immunobiology of fibrin-based engineered heart tissue.
Stem cells translational medicine Jun, 2015 | Pubmed ID: 25947338
Mesenchymal stromal cell therapy: different sources exhibit different immunobiological properties.
Transplantation Jun, 2015 | Pubmed ID: 26035274
Effective Apical Infection of Differentiated Human Bronchial Epithelial Cells and Induction of Proinflammatory Chemokines by the Highly Pneumotropic Human Adenovirus Type 14p1.
PloS one , 2015 | Pubmed ID: 26168049
Local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2015 | Pubmed ID: 26183619
Advancing knowledge of right ventricular pathophysiology in chronic pressure overload: Insights from experimental studies.
Archives of cardiovascular diseases Oct, 2015 | Pubmed ID: 26184869
Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats.
American journal of physiology. Heart and circulatory physiology Oct, 2015 | Pubmed ID: 26254329
Distal Airway Stem Cells are Essential for Lung Regeneration.
Transplantation Aug, 2015 | Pubmed ID: 26308298
Sex Differences in Immunology: More Severe Development of Experimental Pulmonary Hypertension in Male Rats Exposed to Vascular Endothelial Growth Factor Receptor Blockade.
BioMed research international , 2015 | Pubmed ID: 26421302
miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.
Cardiovascular research May, 2016 | Pubmed ID: 26865549
The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation.
Transplantation May, 2016 | Pubmed ID: 26910327
"Bioengineered lungs" Best science paper in JHLT 2014-2015.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Apr, 2016 | Pubmed ID: 27044534
Orthotopic tracheal transplantation using human bronchus: an original xenotransplant model of obliterative airway disorder.
Transplant international : official journal of the European Society for Organ Transplantation Dec, 2016 | Pubmed ID: 27614085
miR-126: a potential new key player in hypoxia and reperfusion?
Annals of translational medicine Oct, 2016 | Pubmed ID: 27826580
Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats - an experimental study.
Transplant international : official journal of the European Society for Organ Transplantation Nov, 2017 | Pubmed ID: 28672061
Differences in Vascular Response between Balloon Overstretch and Stent Overexpansion in Nonatherosclerotic Porcine Coronary Arteries.
Comparative medicine Aug, 2017 | Pubmed ID: 28830582
Sphingosine-1-phosphate receptor 1 regulates neointimal growth in a humanized model for restenosis.
Journal of vascular surgery 12, 2018 | Pubmed ID: 29804740
No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart.
Pharmacology research & perspectives 06, 2018 | Pubmed ID: 29864245
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.
Nature biotechnology 03, 2019 | Pubmed ID: 30778232
De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.
Nature biotechnology Aug, 2019 | Pubmed ID: 31427818
Stanford University School of Medicine
University Heart Center Hamburg
University Hospital Hamburg
TSI-Lab, Germany
University of Hamburg
Cardiovascular Research Center (CVRC) and DZHK University Hamburg
Columbia University
University of California San Francisco (UCSF)
partner site Hamburg/Kiel/Luebeck
University Heart Center
Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research
University of California San Francisco
Columbia College
Xiaoqin Hua1,2,
Tobias Deuse1,2,
Evangelos D. Michelakis3,
Alois Haromy3,
Phil S. Tsao4,
Lars Maegdefessel4,
Reinhold G. Erben5,
Claudia Bergow5,
Boris B. Behnisch6,
Hermann Reichenspurner1,2,
Robert C. Robbins7,
Sonja Schrepfer1,2,7
1University Heart Center Hamburg, TSI-Lab, Germany,
2Cardiovascular Research Center, University of Hamburg,
3Department of Medicine, Cardiology Division, Pulmonary Hypertension Program, University of Alberta,
4Department of Medicine, Stanford University School of Medicine ,
5Department of Biomedical Sciences, Institute of Physiology, Pathophysiology, and Biophysics, University of Veterinary Medicine, Vienna,
6Translumina GmbH, Hechingen,
7Department of Cardiothoracic Surgery, Stanford University School of Medicine
Mandy Stubbendorff*,1,2,
Xiaoqin Hua*,1,2,
Tobias Deuse1,2,3,
Ziad Ali4,5,
Hermann Reichenspurner2,3,
Lars Maegdefessel6,
Robert C. Robbins7,
Sonja Schrepfer1,2,3,4
1Transplant and Stem Cell Immunobiology Lab, Cardiovascular Research Center, University Hospital Hamburg,
2, Cardiovascular Research Center (CVRC) and DZHK University Hamburg,
3Department of Cardiovascular Surgery, University Heart Center Hamburg,
4Center for Interventional Vascular Therapy, Division of Cardiology, Columbia University,
5, Cardiovascular Research Foundation, New York,
6, Karolinska Institute, Stockholm,
7Department of Cardiothoracic Surgery, Stanford University School of Medicine, Falk Cardiovascular Research Center
Dong Wang1,2,3,4,
Grigol Tediashvili1,2,3,
Simon Pecha4,
Hermann Reichenspurner4,
Tobias Deuse1,2,3,4,
Sonja Schrepfer1,2,3,4
1Transplant and Stem Cell Immunobiology Lab, University Heart Center Hamburg,
2Department of Surgery, Transplant and Stem Cell Immunobiology Lab, University of California San Francisco (UCSF),
3Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck,
4Cardiovascular Surgery, University Heart Center Hamburg
Grigol Tediashvili1,2,3,
Dong Wang1,2,3,4,
Hermann Reichenspurner4,
Tobias Deuse1,2,3,4,
Sonja Schrepfer1,2,3,4
1Transplant and Stem Cell Immunobiology Lab, University Heart Center,
2Department of Surgery, Transplant and Stem Cell Immunobiology Lab, University of California San Francisco (UCSF),
3, Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research,
4Cardiovascular Surgery, University Heart Center
Dong Wang*,1,2,
Grigol Tediashvili*,1,2,
Xiaomeng Hu1,2,
Alessia Gravina2,
Sivan G. Marcus1,2,
Hao Zhang4,
Jeffrey E Olgin4,
Tobias Deuse1,2,5,
Sonja Schrepfer1,2,3,5
1Transplant and Stem Cell Immunobiology Lab, University Heart Center,
2Department of Surgery, Transplant and Stem Cell Immunobiology Lab, University of California San Francisco,
3, Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research,
4Division of Cardiology, Cardiovascular Research Institute, University of California San Francisco,
5Cardiovascular Surgery, University Heart Center
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