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ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.
Molecular cell Sep, 2002 | Pubmed ID: 12408825
Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation.
Nature structural & molecular biology Apr, 2005 | Pubmed ID: 15768032
Examining the complexity of human RNA polymerase complexes using HaloTag technology coupled to label free quantitative proteomics.
Journal of proteome research Feb, 2012 | Pubmed ID: 22149079
Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands.
Current chemical genomics , 2012 | Pubmed ID: 23248739
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
The EMBO journal Mar, 2013 | Pubmed ID: 23353889
Isolation of intracellular protein--DNA complexes using HaloCHIP, an antibody-free alternative to chromatin immunoprecipitation.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23436357
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.
Cell Jun, 2013 | Pubmed ID: 23746844
structural Studies of Wnts and identification of an LRP6 binding site.
Structure (London, England : 1993) Jul, 2013 | Pubmed ID: 23791946
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors.
Cell Aug, 2013 | Pubmed ID: 23871696