Center for Regenerative Medicine (CReM),
The Pulmonary Center and Department of Medicine
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Stem cell antigen-1 expression in the pulmonary vascular endothelium.
American journal of physiology. Lung cellular and molecular physiology Jun, 2003 | Pubmed ID: 12611818
Side population cells and Bcrp1 expression in lung.
American journal of physiology. Lung cellular and molecular physiology Jul, 2003 | Pubmed ID: 12626330
Translational physiology: origin and phenotype of lung side population cells.
American journal of physiology. Lung cellular and molecular physiology Sep, 2004 | Pubmed ID: 15047566
Lung stem cells: new paradigms.
Experimental hematology Apr, 2004 | Pubmed ID: 15050743
Embryonic lung side population cells are hematopoietic and vascular precursors.
American journal of respiratory cell and molecular biology Jul, 2005 | Pubmed ID: 15802552
A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity.
Blood Sep, 2005 | Pubmed ID: 15870171
Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2005 | Pubmed ID: 15922964
Failure of bone marrow to reconstitute lung epithelium.
American journal of respiratory cell and molecular biology Oct, 2005 | Pubmed ID: 15961722
Exogenous control of mammalian gene expression via modulation of translational termination.
Nature medicine Sep, 2006 | Pubmed ID: 16892063
Lung stem cells.
Cell and tissue research Jan, 2008 | Pubmed ID: 17805578
Dual-promoter lentiviral system allows inducible expression of noxious proteins in macrophages.
Journal of immunological methods Jan, 2008 | Pubmed ID: 17967462
The prolonged life-span of alveolar macrophages.
American journal of respiratory cell and molecular biology Apr, 2008 | Pubmed ID: 18192503
Another notch in stem cell biology: Drosophila intestinal stem cells and the specification of cell fates.
BioEssays : news and reviews in molecular, cellular and developmental biology Feb, 2008 | Pubmed ID: 18200564
Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells.
American journal of respiratory cell and molecular biology Aug, 2008 | Pubmed ID: 18323534
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette.
Stem cells (Dayton, Ohio) Mar, 2009 | Pubmed ID: 19096035
Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes.
PloS one , 2009 | Pubmed ID: 19415118
Pulmonary alveolar proteinosis: a bench-to-bedside story of granulocyte-macrophage colony-stimulating factor dysfunction.
Chest Aug, 2009 | Pubmed ID: 19666756
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector.
Stem cells (Dayton, Ohio) Jan, 2010 | Pubmed ID: 19904830
Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.
The Journal of clinical investigation Jan, 2010 | Pubmed ID: 20038801
The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors.
Journal of immunology (Baltimore, Md. : 1950) May, 2010 | Pubmed ID: 20357252
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.
Stem cells (Dayton, Ohio) Oct, 2010 | Pubmed ID: 20715179
FOXO1 modulates osteoblast differentiation.
Bone May, 2011 | Pubmed ID: 21281751
Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.
The Journal of clinical investigation Jun, 2011 | Pubmed ID: 21537085
Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
Proceedings of the American Thoracic Society Jun, 2011 | Pubmed ID: 21653526
A shift from cell cultures to creatures: in vivo imaging of small animals in experimental regenerative medicine.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2011 | Pubmed ID: 21952170
Programmatic change: lung disease research in the era of induced pluripotency.
American journal of physiology. Lung cellular and molecular physiology Dec, 2011 | Pubmed ID: 21984571
Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry.
The Journal of physiology Dec, 2011 | Pubmed ID: 22025662
Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.
Biochemical and biophysical research communications Jan, 2012 | Pubmed ID: 22142851
Are embryonic stem and induced pluripotent stem cells the same or different? Implications for their potential therapeutic use.
Cell cycle (Georgetown, Tex.) Jan, 2012 | Pubmed ID: 22186787
Case records of the Massachusetts General Hospital. Case 2-2012. A 63-year-old woman with dyspnea and rapidly progressive respiratory failure.
The New England journal of medicine Jan, 2012 | Pubmed ID: 22256809
Maintenance and repair of the lung endothelium does not involve contributions from marrow-derived endothelial precursor cells.
American journal of respiratory cell and molecular biology Jul, 2012 | Pubmed ID: 22323363
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells.
Cell stem cell Apr, 2012 | Pubmed ID: 22482503
Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells.
Cell stem cell Apr, 2012 | Pubmed ID: 22482505
Next-generation regeneration: the hope and hype of lung stem cell research.
American journal of respiratory and critical care medicine Jun, 2012 | Pubmed ID: 22517787
Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells.
Circulation Oct, 2012 | Pubmed ID: 22914687
The Transcription Factors Grainyhead-like 2 and NK2-Homeobox 1 Form a Regulatory Loop That Coordinates Lung Epithelial Cell Morphogenesis and Differentiation.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22955271
The 2012 Nobel Prize in physiology or medicine: democratizing pluripotency for lung researchers.
American journal of respiratory and critical care medicine Dec, 2012 | Pubmed ID: 23204376
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.
The Journal of general physiology Jan, 2013 | Pubmed ID: 23277474
Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2013 | Pubmed ID: 23403494
The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.
Blood Jul, 2013 | Pubmed ID: 23723449
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
Cell stem cell Jun, 2013 | Pubmed ID: 23746980
Lung regeneration: mechanisms, applications and emerging stem cell populations.
Nature medicine Aug, 2014 | Pubmed ID: 25100528
Derivation of Endodermal Progenitors From Pluripotent Stem Cells.
Journal of cellular physiology Feb, 2015 | Pubmed ID: 25160562
Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.
Stem cell reports Apr, 2015 | Pubmed ID: 25772471
Embryonic and induced pluripotent stem cells for lung regeneration.
Annals of the American Thoracic Society Mar, 2015 | Pubmed ID: 25830836
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.
Stem cell reports May, 2015 | Pubmed ID: 25843048
Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.
Cell stem cell Nov, 2015 | Pubmed ID: 26593959
Mouse ESC Differentiation to Nkx2.1+ Lung and Thyroid Progenitors.
Bio-protocol Nov, 2012 | Pubmed ID: 27453901
Regenerative therapy for hypothyroidism: Mechanisms and possibilities.
Molecular and cellular endocrinology 04, 2017 | Pubmed ID: 27876515
Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.
Cell stem cell 06, 2017 | Pubmed ID: 28366587
Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.
The Journal of clinical investigation Jun, 2017 | Pubmed ID: 28463226
Vascular smooth muscle cells derived from inbred swine induced pluripotent stem cells for vascular tissue engineering.
Biomaterials Dec, 2017 | Pubmed ID: 28942128
Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification.
Development (Cambridge, England) 11, 2017 | Pubmed ID: 28947536
Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.
Cell stem cell 10, 2017 | Pubmed ID: 28965766
Claudin-18: unexpected regulator of lung alveolar epithelial cell proliferation.
The Journal of clinical investigation 03, 2018 | Pubmed ID: 29400691
Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.
Stem cell reports 05, 2018 | Pubmed ID: 29657097
Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.
Journal of immunology (Baltimore, Md. : 1950) 04, 2019 | Pubmed ID: 30796179
Generation of a Purified iPSC-Derived Smooth Muscle-like Population for Cell Sheet Engineering.
Stem cell reports 09, 2019 | Pubmed ID: 31422908
Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells.
Nature protocols 12, 2019 | Pubmed ID: 31732721
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.
Cell stem cell 04, 2020 | Pubmed ID: 32004478
The in vivo genetic program of murine primordial lung epithelial progenitors.
Nature communications 01, 2020 | Pubmed ID: 32005814
Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.
Cell stem cell 10, 2020 | Pubmed ID: 32891189
SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Cell stem cell 12, 2020 | Pubmed ID: 32979316
Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration.
Annual review of physiology 02, 2021 | Pubmed ID: 33074772
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.
Cell stem cell 01, 2021 | Pubmed ID: 33098807
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Molecular cell 12, 2020 | Pubmed ID: 33259812
Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine.
Frontiers in endocrinology , 2021 | Pubmed ID: 33959101
Differentiation of human pluripotent stem cells into functional airway basal stem cells.
STAR protocols 09, 2021 | Pubmed ID: 34355203
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
Proceedings of the National Academy of Sciences of the United States of America 09, 2021 | Pubmed ID: 34413211
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Cell reports Aug, 2021 | Pubmed ID: 34469722
Editorial: Progenitors and Stem Cells in Thyroid Development, Disease, and Regeneration.
Frontiers in endocrinology , 2022 | Pubmed ID: 35211095
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Nature Apr, 2022 | Pubmed ID: 35355013