Department of Psychiatry
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The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedure.
Psychopharmacology May, 2009 | Pubmed ID: 19132351
Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism.
Behavioural brain research Jul, 2009 | Pubmed ID: 19428636
Dopamine, behavioral economics, and effort.
Frontiers in behavioral neuroscience , 2009 | Pubmed ID: 19826615
Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonists.
Psychopharmacology Jul, 2011 | Pubmed ID: 21347642
The behavioral pharmacology of effort-related choice behavior: dopamine, adenosine and beyond.
Journal of the experimental analysis of behavior Jan, 2012 | Pubmed ID: 22287808
The novel adenosine A(2A) antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions.
Pharmacology, biochemistry, and behavior Oct, 2012 | Pubmed ID: 22705392
Dopaminergic modulation of effort-related choice behavior as assessed by a progressive ratio chow feeding choice task: pharmacological studies and the role of individual differences.
PloS one , 2012 | Pubmed ID: 23110135
Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors.
Neuroscience and biobehavioral reviews Nov, 2013 | Pubmed ID: 23583616
Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task.
Psychopharmacology Feb, 2014 | Pubmed ID: 24136220
Effort-related motivational effects of the VMAT-2 inhibitor tetrabenazine: implications for animal models of the motivational symptoms of depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2013 | Pubmed ID: 24305809
The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: reversal with antidepressant drugs.
PloS one , 2014 | Pubmed ID: 24937131
The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists.
Pharmacology, biochemistry, and behavior Aug, 2015 | Pubmed ID: 26022661
Muscarinic, but not nicotinic, acetylcholine receptor blockade in the ventral tegmental area attenuates cue-induced sucrose-seeking.
Behavioural brain research Sep, 2015 | Pubmed ID: 26026787
1Interdepartmental Neuroscience Program, Yale University,
2Department of Biotechnical and Clinical Laboratory Sciences, School of Medicine and Biomedical Sciences, University at Buffalo,
3Department of Psychiatry, Yale School of Medicine,
4Department of Cellular and Molecular Physiology, Yale School of Medicine