Department of Medical Biotechnology and Translational Medicine
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SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth.
The Journal of investigative dermatology Nov, 2007 | Pubmed ID: 17625595
The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host.
Cancer metastasis reviews Sep, 2008 | Pubmed ID: 18459035
The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host.
Cancer metastasis reviews Dec, 2008 | Pubmed ID: 18542844
Matricellular proteins and inflammatory cells: a task force to promote or defeat cancer?
Cytokine & growth factor reviews Feb, 2010 | Pubmed ID: 20006533
SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF.
American journal of physiology. Gastrointestinal and liver physiology May, 2011 | Pubmed ID: 21311029
SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis.
The Journal of investigative dermatology Dec, 2011 | Pubmed ID: 21850018
A Tumor-stroma Targeted Oncolytic Adenovirus Replicated in Human Ovary Cancer Samples and Inhibited Growth of Disseminated Solid Tumors in Mice.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2012 | Pubmed ID: 22948673
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
Breast cancer research : BCR Sep, 2014 | Pubmed ID: 25248717
ICln: a new regulator of non-erythroid 4.1R localisation and function.
PloS one , 2014 | Pubmed ID: 25295618
Customized patterned substrates for highly versatile correlative light-scanning electron microscopy.
Scientific reports Nov, 2014 | Pubmed ID: 25391455
INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model.
Scientific reports Apr, 2016 | Pubmed ID: 27079797
Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes.
Nature communications Jul, 2016 | Pubmed ID: 27377421
MEGA-V: detection of variant gene sets in patient cohorts.
Bioinformatics (Oxford, England) Apr, 2017 | Pubmed ID: 28003259
Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC.
Molecular cancer research : MCR Mar, 2017 | Pubmed ID: 28031408
Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission.
Nature communications Mar, 2017 | Pubmed ID: 28262662
Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1.
Oncotarget Jun, 2017 | Pubmed ID: 28430577
1Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano,
2Department of Neuroscience; Department of Cell Biology, Howard Hughes Medical Institute, Yale University School of Medicine,
3Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine,
4Department of BioSciences, Università degli Studi di Milano