Department of Chemical and Physical Sciences
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Selective detection of tyrosine-containing proximally phosphorylated motifs using an antenna-free Tb³⁺ luminescent sensor.
Chemical communications (Cambridge, England) Apr, 2015 | Pubmed ID: 25785373
A STAT inhibitor patent review: progress since 2011.
Expert opinion on therapeutic patents , 2015 | Pubmed ID: 26394986
A tool for the selective sequestration of ATP and PPi to aid in-solution phosphopeptide detection assays.
The Analyst Feb, 2016 | Pubmed ID: 26643551
Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics.
Molecular cancer therapeutics May, 2016 | Pubmed ID: 26873728
Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 1).
Chembiochem : a European journal of chemical biology Apr, 2016 | Pubmed ID: 27027879
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.
ChemMedChem Apr, 2016 | Pubmed ID: 27028877
Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2).
ChemMedChem Apr, 2016 | Pubmed ID: 27061459
A selective inhibitor of the UFM1-activating enzyme, UBA5.
Bioorganic & medicinal chemistry letters 09, 2016 | Pubmed ID: 27520940
Strategies for over-expression and purification of recombinant full length STAT5B in Escherichia coli.
Protein expression and purification 01, 2017 | Pubmed ID: 27590918
Characterization and application studies of ProxyPhos, a chemosensor for the detection of proximally phosphorylated peptides and proteins in aqueous solutions.
The Analyst Jun, 2017 | Pubmed ID: 28574079
High-throughput thermofluor-based assays for inhibitor screening of STAT SH2 domains.
Journal of pharmaceutical and biomedical analysis Sep, 2017 | Pubmed ID: 28600954
Structure-activity relationship study of ProxyPhos chemosensors for the detection of proximal phosphorylation and other phosphate species.
The Analyst Oct, 2017 | Pubmed ID: 28930308
ProxyPhos sensors for the detection of negatively charged membranes.
The Analyst Nov, 2017 | Pubmed ID: 29098228
A functional in vitro assay for screening inhibitors of STAT5B phosphorylation.
Journal of pharmaceutical and biomedical analysis Jan, 2019 | Pubmed ID: 30223143
PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication.
Cancers Feb, 2019 | Pubmed ID: 30717267
Mulu Geletu*,1,2,
Victoria Hoskin*,1,
Blerta Starova*,1,3,
Maximilian Niit1,4,
Hanad Adan1,
Bruce Elliott1,
Patrick Gunning2,
Leda Raptis1
1Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine, Queen's University, Kingston,
2Department of Chemical and Physical Sciences, University of Toronto, Mississauga,
3Department of Laboratory Medicine, Brampton Civic Hospital Campus, William Osler Health System,
4, Latner Thoracic Surgery Research Laboratories