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Department of Biochemistry
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Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.
European journal of haematology Mar, 2009 | Pubmed ID: 19067737
Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options.
European journal of cancer (Oxford, England : 1990) Nov, 2009 | Pubmed ID: 19729298
Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.
Neoplasia (New York, N.Y.) Apr, 2010 | Pubmed ID: 20360943
The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2010 | Pubmed ID: 20570929
Nitric oxide-donating acetylsalicylic acid induces apoptosis in chronic lymphocytic leukemia cells and shows strong antitumor efficacy in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2011 | Pubmed ID: 21097689
Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells.
Molecular medicine (Cambridge, Mass.) , 2011 | Pubmed ID: 21519633
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.
Molecular and cellular biology Sep, 2011 | Pubmed ID: 21746883
Temple University
Karthik Mallilankaraman1,
Rajesh Kumar Gandhirajan1,
Brian J. Hawkins2,
Muniswamy Madesh1
1Department of Biochemistry, Temple University ,
2Department of Anesthesiology and Pain Medicine, University of Washington
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