Department of Radiation Oncology
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Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
Mutation research Mar, 2009 | Pubmed ID: 18948225
Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.
The Journal of clinical investigation May, 2009 | Pubmed ID: 19425167
DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.
Cancer research Aug, 2010 | Pubmed ID: 20631074
Tumors induce complex DNA damage in distant proliferative tissues in vivo.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2010 | Pubmed ID: 20855610
Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.
Neuro-oncology May, 2011 | Pubmed ID: 21398658
Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Jun, 2011 | Pubmed ID: 21704410
The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Jun, 2011 | Pubmed ID: 21719137
p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage.
Cancer research Aug, 2011 | Pubmed ID: 21742769
Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer.
PloS one , 2011 | Pubmed ID: 21912620
Molecular markers for cancer prognosis and treatment: have we struck gold?
Cancer letters Dec, 2012 | Pubmed ID: 22120674
Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors.
Frontiers in molecular neuroscience , 2011 | Pubmed ID: 22275880
Kinomic profiling approach identifies Trk as a novel radiation modulator.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Jun, 2012 | Pubmed ID: 22561027
MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2012 | Pubmed ID: 22619307
Epigenetic inactivation of DNA repair in breast cancer.
Cancer letters May, 2012 | Pubmed ID: 22634493
Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition.
Cancer research Nov, 2012 | Pubmed ID: 22962264
HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair.
Cancer research Sep, 2012 | Pubmed ID: 22987487
Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells.
PloS one , 2012 | Pubmed ID: 23071597
Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2012 | Pubmed ID: 23147994
1Department of Radiation Oncology, University of Alabama-Birmingham,
2Department of Radiation Oncology, The Ohio State University Medical School,
3Department of Cell Biology, and Pharmacology and Toxicology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, University of Alabama-Birmingham