Section for Immunology,
Joslin Diabetes Center,
Section for Immunology, Joslin Diabetes Center
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T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice.
The Journal of experimental medicine Jul, 2002 | Pubmed ID: 12093873
Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2004 | Pubmed ID: 14694195
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.
The Journal of clinical investigation Dec, 2010 | Pubmed ID: 21099114
PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant.
Diabetes Mar, 2013 | Pubmed ID: 23193190
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection.
Immunity May, 2015 | Pubmed ID: 25979422
Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2015 | Pubmed ID: 26404487
Ptpn22 Modifies Regulatory T Cell Homeostasis via GITR Upregulation.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2016 | Pubmed ID: 26810223
The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells.
Genes and immunity 06, 2016 | Pubmed ID: 27029527
In Vivo Enrichment of Diabetogenic T Cells.
Diabetes 08, 2017 | Pubmed ID: 28396510
Peripherally induced regulatory T cells contribute to the control of autoimmune diabetes in the NOD mouse model.
European journal of immunology 07, 2018 | Pubmed ID: 29604048
Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity.
Science signaling 06, 2018 | Pubmed ID: 29895617
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes.
Nature metabolism May, 2019 | Pubmed ID: 31423480
The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model.
Genes and immunity 01, 2020 | Pubmed ID: 31435002
Anti-CD3 Antibody for the Prevention of Type 1 Diabetes: A Story of Perseverance.
Biochemistry 10, 2019 | Pubmed ID: 31523950
Regulation of B cell homeostasis by Ptpn22 contributes to type 1 diabetes in NOD mice.
Endocrine 03, 2020 | Pubmed ID: 31732921
Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes.
Nature metabolism 09, 2020 | Pubmed ID: 32719542
Genetic Modifiers of Thymic Selection and Central Tolerance in Type 1 Diabetes.
Frontiers in immunology , 2022 | Pubmed ID: 35464420
Toward a precision medicine approach for autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America 05, 2022 | Pubmed ID: 35522710
CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells.
Frontiers in immunology , 2022 | Pubmed ID: 35720357