Mouse Cardiac Arrest Model for Brain Imaging and Brain Physiology Monitoring During Ischemia and ResuscitationRan Li 1, Weina Duan 1, Dong Zhang 2, Ulrike Hoffmann 3, Junjie Yao 2, Wei Yang 1, Huaxin Sheng 1
1Multidisciplinary Brain Protection Program, Department of Anesthesiology, Duke University Medical Center, 2Department of Biomedical Engineering, Duke University, 3Department of Anesthesiology and Pain Management, UT Southwestern University Medical Center
This protocol demonstrates a unique mouse model of asphyxia cardiac arrest that does not require chest compression for resuscitation. This model is useful for monitoring and imaging the dynamics of brain physiology during cardiac arrest and resuscitation.
