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Protatonce Ltd, Demokritos Science Park

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

A GMP-Compliant Procedure for the Generation of Gene-Modified T cells
Nikolaos Savvopoulos 1, Klearchos Stampolitis 1, Georgios Alexandropoulos 1, Dionysia Kefala 1, Memnon Lysandrou 1, Vassiliki Zacharioudaki 1, Nikos Tsolakos 2, Alexandros Spyridonidis 1
1Institute of Cell Therapy, Bone Marrow Transplantation Lab, Department of Medicine, University of Patras, 2Protatonce Ltd, Demokritos Science Park

This protocol outlines the process of transducing primary human T cells with a gene of interest, ensuring compatibility with Good Manufacturing Practice (GMP) standards.

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