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Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
Mar Janna Dahl 1, Stefano Robbiani 2, Chiara Veneroni 2, Anna Lavizzari 3, Sebastian Amos 1, Gabrielle C. Musk 1,4, Helen Kershaw 4, Jonathan W. Davis 5,6, Fabio Mosca 3, Peter B. Noble 1, Raffaele Dellacà *2, J. Jane Pillow *1,6
1School of Human Sciences, The University of Western Australia, 2Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, 3NICU, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 4Animal Care Services, The University of Western Australia, 5Medical School, University of Western Australia, 6Telethon Kids Institute

Optimization of occlusion pressure and duration required to improve lung hypoplasia with tracheal occlusion is essential to improve in utero corrective treatments for congenital diaphragmatic hernia (CDH). This study reports a new method for continuous measurement of the tracheal pressure in an occluded and unoccluded fetal lamb surgical model of CDH.

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