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St. Paul’s Hospital

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Rachel L Eddy 1,2, George H Xu 3, Jonathon A Leipsic 1,4, Janice M Leung 1,2, Don D Sin 1,2, Chase S Hall 5, Roger C Tam 3,4
1UBC Centre for Heart Lung Innovation, St. Paul’s Hospital, 2Division of Respiratory Medicine, Department of Medicine, University of British Columbia, 3School of Biomedical Engineering, University of British Columbia, 4Department of Radiology, University of British Columbia, 5Division of Pulmonary and Critical Care Medicine, University of Kansas Medical Center

CT and 129Xe MRI provide complementary lung structure-function information that can be exploited for regional analysis using image registration. Here, we provide a protocol that builds from the existing literature for 129Xe MR to CT image registration using open-source platforms.

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