Prediction of Red Blood Cell Antibody Significance Using the Monocyte-Macrophage AssayLindsay K. Hillis 1,2, Selena Cen 2, Clemence Salou 3, Yeniley Ruiz Noa 2, Donald R. Branch 1,2,4
1Department of Laboratory Medicine and Pathobiology, University of Toronto, 2Centre for Innovation, Canadian Blood Services, Keenan Research Centre, 3Polytech Clermont, 4Department of Medicine, University of Toronto
We have developed enhancements and updated methods for the existing monocyte-monolayer assay (MMA), in which macrophages are used to help better predict the clinical relevance of red cell alloantibodies in transfusion medicine and immunology. This assay is named the monocyte-macrophage assay (M-MA).
