Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain InjuryKei Hashimoto 1, Mari Nakashima 1, Yasunori Miyamoto 1, Hiroko Ikeshima-Kataoka 2
1Institute for Human Life Science, Ochanomizu University, 2Kitasato University School of Frontier Engineering
Simplified traumatic brain injury (TBI) models have facilitated the development of therapeutic approaches. This protocol outlines the creation of a stab-wound mouse cortex using needles, enabling the analysis of hemorrhage and inflammation. The stab-wound TBI mouse model offers the advantage of being performed without requiring specialized equipment.
