Artificial Lung Device Priming for In Situ Fiber Bundle Surface GraftingRomario Pusey *1, Sarah Majin 1, Amir Mokhammad 1, Betelihem Fre 1, Kebisha Basukala 1, Chika G. Okwuogori 1, Keith Cook *2,3, Rei Ukita 4, William Grogan 5, David Skoog *2, Kagya Amoako *1
1Department of Chemistry and Chemical & Biomedical Engineering, University of New Haven, 2Advanced Respiratory Technologies, LLC, 3Department of Biomedical Engineering, Carnegie Mellon University, 4Department of Cardiac Surgery, Vanderbilt University Medical Center, 5Auburn University
This study investigated the antifouling activity of artificial lung hollow fibers coated by priming the lung device. While this surface modification of fibers approach is practical, the effectiveness of the coating process depends on the graft coverage across fiber mat layers within the bundle.