Cleveland Clinic London

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Improving Outcomes in Anteromesial Temporal Lobe Resections - A Demonstration of Resecting the Temporal Piriform Cortex
Debayan Dasgupta 1,2, Lawrence P. Binding 1,3, Davide Giampiccolo 1,2,3,4, Roisin Finn 2, Stephen Wastling 5,6, Sjoerd B. Vos 3,6,7, Anna Miserocchi 1,2,4, Andrew W. McEvoy 1,2,4, John S. Duncan 1
1Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, 2Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, 3Department of Computer Science, Centre for Medical Image Computing, University College London, 4Institute of Neuroscience, Cleveland Clinic London, 5Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, 6Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology, University College London, 7Centre for Microscopy, Characterisation, and Analysis, The University of Western Australia

Here, we demonstrate an approach to intraoperative neurosurgical guidance in anteromesial temporal lobe resections, specifically highlighting the use of tractography and anatomical masks to aid safe resection of the temporal portion of the piriform cortex - an area increasingly regarded as a crucial surgical target in drug-resistant mesial temporal lobe epilepsy.

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