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Papanin Institute for Biology of Inland Waters RAS

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Anesthesia-free Heartbeat Measurements in Freely Moving Zebrafish
Alexander Machikhin 1, Artem Slavin 1,2, Anastasia Guryleva 1, Viacheslav Krylov 1,3,4
1Scientific and Technological Centre of Unique Instrumentation of RAS, 2Moscow State University, 3Cherepovets State University, 4Papanin Institute for Biology of Inland Waters RAS

The study aims to develop technology for anesthesia-free heartbeat measurements in moving zebrafish. Our approach combines shortwave-infrared imaging and machine-learning-based tracking of the heart. It is a non-invasive, label-free, and user-friendly technique that suits a wide range of studies on the zebrafish model.

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