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Chemistry

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Sharareh Salar-Behzadi 1,2, Carolina Corzo 1, Peter Laggner 1
1Research Center Pharmaceutical Engineering, GmbH, 2Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology and Biopharmacy, University of Graz

This publication shows the application of x-ray diffraction and differential scanning calorimetry as gold standards for investigating the solid-state of lipid-based excipients (LBEs). Understanding the solid-state alteration in LBEs and its effect on the performance of pharmaceutical products thereof is the key factor for manufacturing robust lipid-based dosage forms.

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