An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA TreatmentMoo Rim Kang *1, Glen Yang *1, Klaus Charisse 2, Hila Epstein-Barash 2, Muthiah Manoharan 2, Long-Cheng Li 1
1Department of Urology and Helen Diller Comprehensive Cancer Center, University of California, San Francisco , 2Alnylam Pharmaceuticals, Inc.
Establishing an orthotopic bladder tumor model to evaluate antitumor effects of intravesically delivered saRNA and monitoring tumor growth by ultrasound and bioluminescent imaging.