Tabriz University (Medical Sciences)

2 ARTICLES PUBLISHED IN JoVE

Biology

Cellular Toxicity of Nanogenomedicine in MCF-7 Cell Line: MTT assay

Somaieh Ahmadian^1,2, Jaleh Barar^1,3, Amir Ata Saei¹, Mohammad Amin Abolghassemi Fakhree², Yadollah Omidi^1,3

¹Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University (Medical Sciences), ²Gifted and Talented Students Office, Educational Development Center, Tabriz University (Medical Sciences), ³School of Advanced Biomedical Sciences, Tabriz University (Medical Sciences)

The MTT assay is an easy and reproducible colorimetric assay for evaluation of cell viability based on reduction of yellow MTT and production of water insoluble purple formazan. Here, the viability of MCF-7 cells upon treatment of nanogenomedicine has been evaluated.

Neuroscience

An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke

Hamdollah Panahpour¹, Mehdi Farhoudi², Yadollah Omidi³, Javad Mahmoudi²

¹Department of Physiology, Medical School, Ardabil University of Medical Sciences, ²Neurosciences Research Center, Tabriz University of Medical Sciences, ³Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences

The overall goal of this procedure is to provide a highly reproducible technique for in vivo assessment of the blood-brain barrier disruption in rat models of ischemic stroke.