Diagenode S.A.

1 ARTICLES PUBLISHED IN JoVE

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Biology

Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells
Geoffrey Berguet 1, Jan Hendrickx 1, Celine Sabatel 1, Miklos Laczik 1, Sharon Squazzo 2, Ignacio Mazon Pelaez 2, Rini Saxena 2, Helene Pendeville 1, Dominique Poncelet 1
1Diagenode S.A., 2Diagenode Inc.

Methods for mapping in vivo protein-DNA interactions are becoming crucial for every aspect of genomic research but they are laborious, costly, and time consuming. Here a commercially available robotic liquid handling system that automates chromatin immunoprecipitation for mapping in vivo protein-DNA interactions with limited amounts of cells is presented.

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