登录

LSU Health Shreveport

1 ARTICLES PUBLISHED IN JoVE

image

Medicine

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
Joshua C. Colvin 1, Donald Sorrells 1, J. Steven Alexander 2
1Department of Surgery, LSU Health Shreveport, 2Department of Molecular and Cellular Physiology, LSU Health Shreveport

Here, we present a protocol for derivatizing medical devices with protein therapeutics by conjugating protein therapeutics to a polyvinyl alcohol membrane casted on medical devices. Conjugation of protein-based therapeutics allows for localized and concentrated delivery and is a cost-effective approach that requires vastly lower drug amounts for dosing while minimizing off-target effects.

JoVE Logo

政策

使用条款

隐私

科研

教育

关于 JoVE

版权所属 © 2025 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。