An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee ExplantsChristian S. Thudium *1, Amalie Engstrom *1,2, Solveig S. Groen 1, Morten A. Karsdal 1, Anne-Christine Bay-Jensen 1
1Nordic Bioscience, 2Department of Biomedical Sciences, University of Copenhagen
Here, we present a protocol describing isolation and culturing of cartilage explants from bovine knees. This method provides an easy and accessible tool to describe tissue changes in response to biological stimuli or novel therapeutics targeting the joint.
