AIT Bioscience

1 ARTICLES PUBLISHED IN JoVE

Biochemistry

Characterizing Cellular Proteins with In-cell Fast Photochemical Oxidation of Proteins

Emily E. Chea¹, Aimee Rinas², Jessica A. Espino¹, Lisa M. Jones¹

¹Department of Pharmaceutical Sciences, University of Maryland Baltimore, ²AIT Bioscience

Here, we characterize protein structure and interaction sites in living cells using a protein footprinting technique termed in-cell fast photochemical oxidation of proteins (IC-FPOP).