Tissue Engineering of Tumor Stromal Microenvironment with Application to Cancer Cell InvasionYi-Zhen Ng 1,2, Andrew P. South 1
1Division of Cancer Research, Ninewells Hospital and Medical School, University of Dundee, 2Institute of Medical Biology, A*Star, Singapore
Tissue engineered fibroblast-derived native matrix is an emerging tool to generate a stromal substrate which supports epithelial cell proliferation and differentiation. Here a protocol applying this methodology to assess the impact of different stromal cell types on tumor cell biology is presented.
