A Method of Permeabilization of Drosophila Embryos for Assays of Small Molecule ActivityMatthew D. Rand 1
1Department of Environmental Medicine, University of Rochester School of Dentistry and Medicine
Introduction of small molecules to the developing Drosophila embryo offers great potential for characterizing biological activity of novel compounds, drugs, and toxins as well as for probing fundamental developmental pathways. Methods described herein outline steps that overcome natural barriers to this approach, expanding the utility of the Drosophila embryo model.
