Sorbonne Universités, UPMC Univ Paris 06, CR7

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Tracking Mouse Bone Marrow Monocytes In Vivo

Pauline Hamon¹, Mathieu Paul Rodero¹, Christophe Combadière¹, Alexandre Boissonnas¹

¹Centre d'Immunologie et des Maladies Infectieuses (CIMI), INSERM, U1135, CNRS, ERL 8255, Sorbonne Universités, UPMC Univ Paris 06, CR7

Monocytes are key regulators of innate immunity and play a critical role in the renewal of the peripheral mononuclear phagocytic system and in case of inflammation. This manuscript describes the procedure of real time imaging of the mouse calvaria bone marrow to study the monocyte mobilisation mechanism.