Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemiaYu Ouyang 1, Martin S. Judenhofer 1, Jeffrey H. Walton 1,2, Jan Marik 3, Simon P. Williams 3, Simon R. Cherry 1,4
1Department of Biomedical Engineering, University of California, Davis, 2Nuclear Magnetic Resonance Facility, University of California, Davis, 3Biomedical Imaging, Genentech, Inc, 4Department of Radiology, University of California, Davis
The method presented here uses simultaneous positron emission tomography and magnetic resonance imaging. In the cerebral hypoxia-ischemia model, dynamic changes in diffusion and glucose metabolism occur during and after injury. The evolving and irreproducible damage in this model necessitates simultaneous acquisition if meaningful multi-modal imaging data are to be acquired.
