Texas Children’s Hospital
2 ARTICLES PUBLISHED IN JoVE
Bioengineering
Preparation of Monodomain Liquid Crystal Elastomers and Liquid Crystal Elastomer Nanocomposites
Hojin Kim 1, Bohan Zhu 1, Huiying Chen 2, Oluwatomiyin Adetiba 2, Aditya Agrawal 1, Pulickel Ajayan 3, Jeffrey G. Jacot 2,4, Rafael Verduzco 1,3
1Chemical and Biomolecular Engineering, Rice University, 2Bioengineering, Rice University, 3Materials Sciences and NanoEngineering, Rice University, 4Congenital Heart Surgery Services, Texas Children’s Hospital
We demonstrate the preparation of siloxane-based and epoxy-based liquid crystal elastomers (LCEs) and LCE nanocomposites. The LCEs are characterized with respect to reversible strain, liquid crystal ordering, and stiffness. As a potential application, we demonstrate their use as shape-responsive substrates in a custom device for active cell culture.
Medicine
Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Alexandra L. Gannon 1,2, Shaji K. Chacko 3, Inka C. Didelija 3, Juan C. Marini 3,4, Chellakkan S. Blesson 1,2
1Department of Reproductive Endocrinology and Infertility, Baylor College of Medicine, 2Family Fertility Center, Texas Children’s Hospital, 3Children’s Nutrition Research Center, Baylor College of Medicine, 4Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine
This study describes the direct measurement of hepatic glucose production in a polycystic ovary syndrome mouse model by using a stable isotopic glucose tracer via tail vein in both fasting and glucose-rich states in tandem.
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