Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the LiverEleonora M. de Leede 1, Mark C. Burgmans 2, Christian H. Martini 3, Fred G. J. Tijl 4, Arian R. van Erkel 2, Jaap Vuyk 3, Ellen Kapiteijn 5, Cornelis Verhoef 6, Cornelis J. H. van de Velde 1, Alexander L. Vahrmeijer 1
1Department of Surgery, Leiden University Medical Centre, 2Department of Radiology, Leiden University Medical Centre, 3Department of Anesthesiology, Leiden University Medical Centre, 4Department of Extracorporeal Circulation, Leiden University Medical Centre, 5Department of Medical Oncology, Leiden University Medical Centre, 6Department of Surgery, Erasmus MC Cancer Institute
In this manuscript, we describe percutaneous isolated hepatic perfusion with simultaneous chemofiltration as treatment for unresectable liver metastases. This procedure is performed under general anaesthesia in the angiosuite by an experienced team, consisting of an interventional radiologist, a clinical perfusionist and anaesthesiologist.