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Boston Children’s Hospital, Harvard Medical School

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
Elizabeth Peruski Canovic 1, Bo Qing 2, Aleksandar S. Mijailovic 3, Anna Jagielska 2, Matthew J. Whitfield 2, Elyza Kelly 4, Daria Turner 4, Mustafa Sahin 4, Krystyn J. Van Vliet 1,2
1Department of Materials Science and Engineering, Massachusetts Institute of Technology, 2Department of Biological Engineering, Massachusetts Institute of Technology, 3Department of Mechanical Engineering, Massachusetts Institute of Technology, 4Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children’s Hospital, Harvard Medical School

We present a set of techniques to characterize the viscoelastic mechanical properties of brain at the micro-, meso-, and macro-scales.

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