Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial PneumoniaTravis B. Nielsen 1, Jun Yan 1, Brian Luna 1, Brad Spellberg 1,2
1Department of Molecular Microbiology and Immunology, University of Southern California, 2Division of Infectious Diseases, Department of Medicine, LAC+USC Medical Center
Infectious pneumonia is among the most common infections in human. An appropriate in vivo model is critical for understanding disease pathogenesis and testing the efficacy of novel therapeutics. With this murine oropharyngeal aspiration pneumonia model, one can examine the pathogenesis and new treatments against these deadly infections.
