AIT Austrian Institute of Technology GmbH

1 ARTICLES PUBLISHED IN JoVE

Chemistry

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

¹Molecular Diagnostics, Centre for Health and Bioresources, AIT Austrian Institute of Technology GmbH

Here, a protocol for the protection of DNA origami nanostructures in Mg-depleted and nuclease-rich media using natural cationic polysaccharide chitosan and synthetic linear polyethyleneimine (LPEI) coatings is presented.