Jacobs School of Medicine and Biomedical Science

1 ARTICLES PUBLISHED IN JoVE

Behavior

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Matthew J. McGuire¹, Steven M. Gertz¹, Jolie D. McCutcheon², Chelsea R. Richardson³, David J. Poulsen¹

¹Department of Neurosurgery, Jacobs School of Medicine and Biomedical Science, ²Comparative Medicine Laboratory Animal Facilities, University at Buffalo, ³emka Technologies

Here we present a protocol to induce severe TBI with the lateral fluid percussion injury (FPI) model in adult, male Wistar rats. We also demonstrate the use of a wireless telemetry system to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis.