University of Copenhagen (UCPH)

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

Decellularization of the Murine Cardiopulmonary Complex

Alejandro E. Mayorca-Guiliani¹, Maria Rafaeva¹, Oliver Willacy¹, Chris D. Madsen², Raphael Reuten¹, Janine T. Erler¹

¹Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), ²Department of Laboratory Medicine, Division of Translational Cancer Research, Lund University

This protocol aims to decellularize the heart and lungs of mice. The resulting extracellular matrix (ECM) scaffolds can be immunostained and imaged to map the location and topology of their components.