Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/ReperfusionChristoph R. Behem 1, Till Friedheim 1, Sabine H. Wipper 2, Hans O. Pinnschmidt 3, Michael F. Graessler 1, Catharina Gaeth 4, Hannes Holthusen 1, Adina Rapp 5, Timo Suntrop 1, Josephina Haunschild 6, Christian D. Etz 6, Constantin J. C. Trepte 1
1Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 2University Department for Vascular Surgery and Department of Operative Medicine, Medical University of Innsbruck, 3Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 4Department of Vascular Medicine, University Heart and Vascular Center Hamburg (UHZ), 5Department of Cardiology, Rostock University Medical Center, 6University Department for Cardiac Surgery, Heart Center Leipzig
Spinal cord microcirculation plays a pivotal role in spinal cord injury. Most methods do not allow real-time assessment of spinal cord microcirculation, which is essential for the development of microcirculation-targeted therapies. Here, we propose a protocol using Laser-Doppler-Flow Needle probes in a large animal model of ischemia/reperfusion.
