Design of a Biaxial Mechanical Loading Bioreactor for Tissue EngineeringBahar Bilgen 1,2, Danielle Chu 3, Robert Stefani 1, Roy K. Aaron 1,2
1Department of Orthopaedics, The Warren Alpert Brown Medical School of Brown University and the Rhode Island Hospital, 2Center for Restorative and Regenerative Medicine, VA Medical Center, Providence, RI, 3University of Texas Southwestern Medical Center
We designed a novel mechanical loading bioreactor that can apply uniaxial or biaxial mechanical strain to a cartilage biocomposite prior to transplantation into an articular cartilage defect.