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Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

DOI :

10.3791/50387-v

April 25th, 2013

April 25th, 2013

14,054 Views

1Department of Orthopaedics, The Warren Alpert Brown Medical School of Brown University and the Rhode Island Hospital, 2Center for Restorative and Regenerative Medicine, VA Medical Center, Providence, RI, 3University of Texas Southwestern Medical Center

We designed a novel mechanical loading bioreactor that can apply uniaxial or biaxial mechanical strain to a cartilage biocomposite prior to transplantation into an articular cartilage defect.

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