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Chapter 12

Aldehydes and Ketones

醛和酮的结构
醛和酮的结构
Vanillin—a flavoring agent in vanilla, cinnamaldehyde—a molecule responsible for the distinct smell of cinnamon, and acetone—a ...
IUPAC 醛类命名法
IUPAC 醛类命名法
Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic ...
IUPAC 酮的命名法
IUPAC 酮的命名法
Like aldehydes, ketones are named using IUPAC rules; in this case, by replacing “e” in the name of the longest hydrocarbon chain with ...
醛类和酮类的俗名
醛类和酮类的俗名
Some common aldehydes and ketones are popularly known by their common names used historically and predate the IUPAC nomenclature.    Common ...
醛和酮的红外和紫外-可见光谱
醛和酮的红外和紫外-可见光谱
Infrared spectroscopy, also known as vibrational spectroscopy, is mainly used to determine the types of bonds and functional groups in molecules. In ...
醛和酮的 NMR 波谱和质谱
醛和酮的 NMR 波谱和质谱
In aldehydes, the hydrogen atom connected to the carbonyl carbon helps distinguish aldehydes from other carbonyl compounds using ¹H NMR spectroscopy. ...
从醇、烯烃和炔烃制备醛和酮
从醇、烯烃和炔烃制备醛和酮
Aldehydes and ketones are prepared from alcohols, alkenes, and alkynes via different reaction pathways. Alcohols are the most commonly used substrates for ...
从腈和羧酸制备醛和酮
从腈和羧酸制备醛和酮
Although it is possible to reduce a carboxylic acid to an aldehyde, strong reducing agents, like lithium aluminum hydride (LAH), prohibit a controlled ...
从羧酸衍生物制备醛和酮
从羧酸衍生物制备醛和酮
Aldehydes are more reactive than carboxylic acids and hence, can get over-reduced to alcohol in the presence of strong reducing agents. Therefore, ...
羰基的亲核加成:一般机制
羰基的亲核加成:一般机制
The carbonyl carbon in an aldehyde or ketone is the site of a nucleophilic attack due to its electron-deficient nature. Depending on the strength of the ...
醛和酮与水:水合物的形成
醛和酮与水:水合物的形成
An oxygen-based nucleophile, like water, can undergo addition reactions with aldehydes and ketones. The reaction leads to the formation of hydrates, also ...
醛类和酮类与醇类:半缩醛形成
醛类和酮类与醇类:半缩醛形成
Similar to water, alcohols can add to the carbonyl carbon of the aldehydes and ketones. The addition of one molecule of alcohol to the carbonyl compound ...
醛类和酮类的保护基团:简介
醛类和酮类的保护基团:简介
Protecting groups are compounds that can bind to a specific functional group in the presence of other functional groups to protect them from undesired ...
缩醛和硫代缩醛作为醛和酮的保护基团
缩醛和硫代缩醛作为醛和酮的保护基团
Acetals are formed by reacting two equivalents of alcohol with carbonyl compounds like aldehydes or ketones. Acetals are unaffected by bases, ...
醛和酮与 HCN:氰醇形成概述
醛和酮与 HCN:氰醇形成概述
Cyanohydrins are compounds that contain –CN and –OH groups on the same carbon atom. They are formed by the nucleophilic addition of the ...
醛和酮与 HCN:氰醇形成机制
醛和酮与 HCN:氰醇形成机制
Cyanohydrins are formed when cyanide nucleophiles and carbonyl compounds like aldehydes and ketones react. A strong base, the cyanide ion, catalyzes ...
醛和酮制烯烃:Wittig 反应概述
醛和酮制烯烃:Wittig 反应概述
The Wittig reaction is the conversion of carbonyl compounds—aldehydes and ketones—to alkenes using phosphorus ylides, or the Wittig reagent. ...
醛和酮制烯烃:Wittig 反应机理
醛和酮制烯烃:Wittig 反应机理
The Wittig reaction, which converts aldehydes or ketones to alkenes using phosphorus ylides, proceeds through a nucleophilic addition‒elimination ...
醛和酮与胺:亚胺和烯胺的形成概述
醛和酮与胺:亚胺和烯胺的形成概述
Primary amines react with carbonyl compounds—aldehydes and ketones—to generate imines. Imines consist of a C=N double bond and are named ...
醛和酮与胺:亚胺形成机制
醛和酮与胺:亚胺形成机制
Imine formation involves the addition of carbonyl compounds to a primary amine. It begins with the generation of carbinolamine through a series of steps ...
醛和酮与胺:烯胺形成机制
醛和酮与胺:烯胺形成机制
Enamine formation involves the addition of carbonyl compounds to a secondary amine through a series of reactions. The mechanism begins with the generation ...
醛和酮制烷烃:Wolff-Kishner 还原
醛和酮制烷烃:Wolff-Kishner 还原
Wolff–Kishner reduction involves converting aldehydes and ketones to alkanes using hydrazine and a base. The reaction converts a carbonyl group to a ...
醛和酮氧化成羧酸
醛和酮氧化成羧酸
Oxidation of aldehydes and ketones results in the formation of carboxylic acids. Aldehydes, bearing hydrogen next to the carbonyl group, are easily ...
醛和酮的反应:Baeyer-Villiger 氧化
醛和酮的反应:Baeyer-Villiger 氧化
Baeyer–Villiger oxidation converts aldehydes to carboxylic acids and ketones to esters. The reaction uses peroxy acids or peracids and is often ...
酮-烯醇互变异构:机制
酮-烯醇互变异构:机制
The keto and enol forms are known as tautomers and they constantly interconvert (or tautomerize) between the two forms under acid or base catalyzed ...
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