June 30th, 2011
•Conserved insulin signaling pathways found in the fruit fly Drosophila melanogaster make this organism a potential tool for modeling metabolic disorders including type II diabetes. To this end, it is critical to establish physiological assays to effectively measure systemic insulin action in peripheral glucose disposal in the adult fly.
Related Videos
High-Resolution Video Tracking of Locomotion in Adult Drosophila Melanogaster
Dissection of Oenocytes from Adult Drosophila melanogaster
A Quantitative Assay for Insulin-expressing Colony-forming Progenitors
Measurement of Lifespan in Drosophila melanogaster
Use of the Ramsay Assay to Measure Fluid Secretion and Ion Flux Rates in the Drosophila melanogaster Malpighian Tubule
Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes
Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets
Optical Cross-Sectional Muscle Area Determination of Drosophila Melanogaster Adult Indirect Flight Muscles
Visualizing and Tracking Endogenous mRNAs in Live Drosophila melanogaster Egg Chambers
Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate