The overall goal of this custom array method for alloantibody detection is to delineate humane leukocyte antigen or HLA epitopes in organ transplantation. This method can help answer key questions in the organ transplantation field about the speci
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Mismatches in human leukocyte antigen (HLA) sequences between organ donor and recipient pairs are the major cause of antibody-mediated rejection in organ transplantation. Here we present the use of custom antigen arrays that are based on individual donors' HLA sequences to probe anti-donor HLA alloantibodies in organ recipients.