Jacob H. Hanna

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Oct4 shuffles Sox partners to direct cell fate.

The expression of the beta cell-derived autoimmune ligand for the killer receptor nkp46 is attenuated in type 2 diabetes.

Deterministic direct reprogramming of somatic cells to pluripotency.

Derivation of novel human ground state naive pluripotent stem cells.

Passage number is a major contributor to genomic structural variations in mouse iPSCs.

Lucky iPSCs.

Stem cells: The quest for the perfect reprogrammed cell.

Hijacked by an oocyte: hierarchical molecular changes in somatic cell nuclear transfer.

SOX17 is a critical specifier of human primordial germ cell fate.

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

CD24 tracks divergent pluripotent states in mouse and human cells.

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors.

Establishing the human naïve pluripotent state.

Failure to replicate the STAP cell phenomenon.

An essential role for UTX in resolution and activation of bivalent promoters.

Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs.

Dynamic stem cell states: naive to primed pluripotency in rodents and humans.

Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution.

Transcriptional programs that control expression of the autoimmune regulator gene Aire.

mA mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.

A multiplexed screening method for pluripotency.

Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression.

OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs.

Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs.

NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis.

RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells.

mA deposition: a boost from TGFβ.

Human Brain Organoids on a Chip Reveal the Physics of Folding.

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies.

The Role of mA/m-RNA Methylation in Stress Response Regulation.

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.

MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.

mA modification controls the innate immune response to infection by targeting type I interferons.

The N-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.

Publisher Correction: m6A modification controls the innate immune response to infection by targeting type I interferons.

Stem Cell-Derived Human Gametes: The Public Engagement Imperative.

Universally non-immunogenic iPSCs.

Stage-specific requirement for Mettl3-dependent mA mRNA methylation during haematopoietic stem cell differentiation.

Deciphering the "mA Code" via Antibody-Independent Quantitative Profiling.

Generation of human endothelium in pig embryos deficient in ETV2.

β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus.

Production and Analysis of Human Primordial Germ Cell-Like Cells.

Context-dependent functional compensation between Ythdf mA reader proteins.

Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.

Principles of signaling pathway modulation for enhancing human naive pluripotency induction.

Modeling genetic epileptic encephalopathies using brain organoids.

The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers.

Mechanism of noncoding RNA-associated N-methyladenosine recognition by an RNA processing complex during IgH DNA recombination.