James C. Garbe

Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter.

Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models.

Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized.

Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis.

Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization.

Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells.

Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.

Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A).

Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells.

Epigenetic regulation of normal human mammary cell type-specific miRNAs.

Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.